2wfa: Difference between revisions
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<StructureSection load='2wfa' size='340' side='right'caption='[[2wfa]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='2wfa' size='340' side='right'caption='[[2wfa]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wfa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2wfa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WFA FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfa OCA], [https://pdbe.org/2wfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wfa RCSB], [https://www.ebi.ac.uk/pdbsum/2wfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfa ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfa OCA], [https://pdbe.org/2wfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wfa RCSB], [https://www.ebi.ac.uk/pdbsum/2wfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfa ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PGMB_LACLA PGMB_LACLA] Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), forming beta-D-glucose 1,6-(bis)phosphate (beta-G16P) as an intermediate. The beta-phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. Glucose or lactose are used in preference to maltose, which is only utilized after glucose or lactose has been exhausted. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose.<ref>PMID:9084169</ref> <ref>PMID:15005616</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Lactococcus lactis]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Alizadeh | [[Category: Alizadeh T]] | ||
[[Category: Baxter | [[Category: Baxter NJ]] | ||
[[Category: Bermel | [[Category: Bermel W]] | ||
[[Category: Blackburn | [[Category: Blackburn GM]] | ||
[[Category: Bowler | [[Category: Bowler MW]] | ||
[[Category: Cliff | [[Category: Cliff MJ]] | ||
[[Category: Hollfelder | [[Category: Hollfelder F]] | ||
[[Category: Hounslow | [[Category: Hounslow AM]] | ||
[[Category: Pollard | [[Category: Pollard S]] | ||
[[Category: Waltho | [[Category: Waltho JP]] | ||
[[Category: Webster | [[Category: Webster CE]] | ||
[[Category: Williams | [[Category: Williams NH]] | ||