Sandbox Reserved 1713: Difference between revisions
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=Anaplastic Lymphoma Kinase= | =Anaplastic Lymphoma Kinase= | ||
<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> | ||
==Introduction== | |||
Anaplastic Lymphoma Kinase is a receptor tyrosine [https://pubmed.ncbi.nlm.nih.gov/32114309/ kinase]. ALK transfers a phosphate group from [https://www.ncbi.nlm.nih.gov/books/NBK553175/ ATP] to a tyrosine residue on an enzyme which activates a signaling cascade, and ALK becomes activated when a ligand called [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789956/ ALKAL] binds to the binding surface on an extracellular domain of ALK. ALK is an integral membrane protein. | Anaplastic Lymphoma Kinase is a receptor tyrosine [https://pubmed.ncbi.nlm.nih.gov/32114309/ kinase]. ALK transfers a phosphate group from [https://www.ncbi.nlm.nih.gov/books/NBK553175/ ATP] to a tyrosine residue on an enzyme which activates a signaling cascade, and ALK becomes activated when a ligand called [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789956/ ALKAL] binds to the binding surface on an extracellular domain of ALK. ALK is an integral membrane protein. | ||