3gh8: Difference between revisions
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='3gh8' size='340' side='right'caption='[[3gh8]], [[Resolution|resolution]] 2.61Å' scene=''> | <StructureSection load='3gh8' size='340' side='right'caption='[[3gh8]], [[Resolution|resolution]] 2.61Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3gh8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3gh8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GH8 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TYI:3,5-DIIODOTYROSINE'>TYI</scene></td></tr> | ||
< | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gh8 OCA], [https://pdbe.org/3gh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gh8 RCSB], [https://www.ebi.ac.uk/pdbsum/3gh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gh8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gh8 OCA], [https://pdbe.org/3gh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gh8 RCSB], [https://www.ebi.ac.uk/pdbsum/3gh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gh8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/IYD1_MOUSE IYD1_MOUSE] Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 38: | Line 37: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Adler | [[Category: Adler JM]] | ||
[[Category: LaRonde-LeBlanc | [[Category: LaRonde-LeBlanc N]] | ||
[[Category: McTamney | [[Category: McTamney PM]] | ||
[[Category: Rokita | [[Category: Rokita SE]] | ||
[[Category: Thomas | [[Category: Thomas SR]] | ||