AMPK signaling pathway: Difference between revisions

New page: <StructureSection load='4rer' size='350' side='right' scene='49/493732/Cv/1' caption='Human AMP-activated protein kinase α1 subunit (deeppink) +β2 subunit (green) +γ1 subunit (cyan) com...
 
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<StructureSection load='4rer' size='350' side='right' scene='49/493732/Cv/1' caption='Human AMP-activated protein kinase α1 subunit (deeppink) +β2 subunit (green) +γ1 subunit (cyan) complex with AMP, staurosporine, cyclodextrin and HEPES (PDB code [[4rer]])'>
<StructureSection load='4rer' size='350' side='right' scene='49/493732/Cv/1' caption='Human AMP-activated protein kinase α1 subunit (deeppink) +β2 subunit (green) +γ1 subunit (cyan) complex with AMP, staurosporine, cyclodextrin and HEPES (PDB code [[4rer]])'>
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[[AMP-activated protein kinase]]
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.


== Function ==
'''AMP-activated protein kinase''' (AMPK) is a [[nuclear receptor]] which regulates cellular uptake of glucose, β-oxidation of fatty acids and biogenesis of glucose transporter thus playing a role in cellular energy homeostasis by phosphorylating key proteins.  In response to low levels of ATP, AMPK activates energy-producing pathways and inhibits energy-consuming pathways.
 
== Disease ==
 
== Relevance ==
 
== Structural highlights ==
 
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.


</StructureSection>
</StructureSection>
== References ==
== References ==
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky