3ddk: Difference between revisions

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<StructureSection load='3ddk' size='340' side='right'caption='[[3ddk]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='3ddk' size='340' side='right'caption='[[3ddk]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ddk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxsackievirus_b3 Coxsackievirus b3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DDK FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ddk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxsackievirus_B3 Coxsackievirus B3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DDK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">3Dpol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12072 Coxsackievirus B3])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ddk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ddk OCA], [https://pdbe.org/3ddk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ddk RCSB], [https://www.ebi.ac.uk/pdbsum/3ddk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ddk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ddk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ddk OCA], [https://pdbe.org/3ddk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ddk RCSB], [https://www.ebi.ac.uk/pdbsum/3ddk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ddk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/Q66338_9ENTO Q66338_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS001676_004_016611]  Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS001676_004_010047]  
[https://www.uniprot.org/uniprot/Q5UEA2_9ENTO Q5UEA2_9ENTO]  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Coxsackievirus b3]]
[[Category: Coxsackievirus B3]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Campagnola, G]]
[[Category: Campagnola G]]
[[Category: Peersen, O B]]
[[Category: Peersen OB]]
[[Category: Scoggin, K E]]
[[Category: Scoggin KE]]
[[Category: Weygandt, M H]]
[[Category: Weygandt MH]]
[[Category: Rna polymerase]]
[[Category: Rna virus]]
[[Category: Transferase]]
[[Category: Viral polymerase]]
[[Category: Viral protein]]

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