7qjs: Difference between revisions

Revision as of 11:47, 28 December 2022

Crystal structure of a cutinase enzyme from Thermobifida fusca YX (705)Crystal structure of a cutinase enzyme from Thermobifida fusca YX (705)

Structural highlights

7qjs is a 2 chain structure with sequence from Thermobifida fusca YX. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, ,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PETH2_THECS Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle (Ref.1). Shows esterase activity towards p-nitrophenol-linked aliphatic esters (pNP-aliphatic esters) (Ref.1, PubMed:23592055). Capable of degrading the plastic poly(ethylene terephthalate) (PET), the most abundant polyester plastic in the world (Ref.1, PubMed:23592055). Capable of degrading the bioplastic poly(lactic acid) (PLLA) (PubMed:28671263).^[1] ^[2] [UniProtKB:A0A0K8P6T7]

References

↑ Herrero Acero E, Ribitsch D, Dellacher A, Zitzenbacher S, Marold A, Steinkellner G, Gruber K, Schwab H, Guebitz GM. Surface engineering of a cutinase from Thermobifida cellulosilytica for improved polyester hydrolysis. Biotechnol Bioeng. 2013 Oct;110(10):2581-90. doi: 10.1002/bit.24930. Epub 2013 , Apr 29. PMID:23592055 doi:http://dx.doi.org/10.1002/bit.24930
↑ Ribitsch D, Hromic A, Zitzenbacher S, Zartl B, Gamerith C, Pellis A, Jungbauer A, Lyskowski A, Steinkellner G, Gruber K, Tscheliessnig R, Acero EH, Guebitz GM. Small cause, large effect: Structural characterization of cutinases from Thermobifida cellulosilytica. Biotechnol Bioeng. 2017 Jul 3. doi: 10.1002/bit.26372. PMID:28671263 doi:http://dx.doi.org/10.1002/bit.26372

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OCA

[1] Herrero Acero E, Ribitsch D, Dellacher A, Zitzenbacher S, Marold A, Steinkellner G, Gruber K, Schwab H, Guebitz GM. Surface engineering of a cutinase from Thermobifida cellulosilytica for improved polyester hydrolysis. Biotechnol Bioeng. 2013 Oct;110(10):2581-90. doi: 10.1002/bit.24930. Epub 2013 , Apr 29. PMID:23592055 doi:http://dx.doi.org/10.1002/bit.24930

[2] Ribitsch D, Hromic A, Zitzenbacher S, Zartl B, Gamerith C, Pellis A, Jungbauer A, Lyskowski A, Steinkellner G, Gruber K, Tscheliessnig R, Acero EH, Guebitz GM. Small cause, large effect: Structural characterization of cutinases from Thermobifida cellulosilytica. Biotechnol Bioeng. 2017 Jul 3. doi: 10.1002/bit.26372. PMID:28671263 doi:http://dx.doi.org/10.1002/bit.26372

[1]

[2]

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7qjs is ON HOLD  until Paper Publication
+==Crystal structure of a cutinase enzyme from Thermobifida fusca YX (705)==
+<StructureSection load='7qjs' size='340' side='right'caption='[[7qjs]], [[Resolution|resolution]] 1.43&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7qjs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca_YX Thermobifida fusca YX]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QJS FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qjs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qjs OCA], [https://pdbe.org/7qjs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qjs RCSB], [https://www.ebi.ac.uk/pdbsum/7qjs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qjs ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PETH2_THECS PETH2_THECS] Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle (Ref.1). Shows esterase activity towards p-nitrophenol-linked aliphatic esters (pNP-aliphatic esters) (Ref.1, PubMed:23592055). Capable of degrading the plastic poly(ethylene terephthalate) (PET), the most abundant polyester plastic in the world (Ref.1, PubMed:23592055). Capable of degrading the bioplastic poly(lactic acid) (PLLA) (PubMed:28671263).<ref>PMID:23592055</ref> <ref>PMID:28671263</ref> [UniProtKB:A0A0K8P6T7]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Thermobifida fusca YX]]
+[[Category: Beckham GT]]
+[[Category: McGeehan JE]]
+[[Category: Shakespeare TJ]]
+[[Category: Zahn M]]

7qjs: Difference between revisions

Revision as of 11:47, 28 December 2022

Crystal structure of a cutinase enzyme from Thermobifida fusca YX (705)Crystal structure of a cutinase enzyme from Thermobifida fusca YX (705)

Structural highlights

Function

References

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7qjs: Difference between revisions

Revision as of 11:47, 28 December 2022

Crystal structure of a cutinase enzyme from Thermobifida fusca YX (705)Crystal structure of a cutinase enzyme from Thermobifida fusca YX (705)

Structural highlights

Function

References

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