ConSurf/Index: Difference between revisions
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The [http://consurf.tau.ac.il ConSurf Server], a project led by Nir Ben-Tal and Tal Pupko (Tel-Aviv University, Israel), colors each amino acid in a protein structure by its level of evolutionary conservation. Functional sites are marked by clusters of '''con'''served '''surf'''ace residues. Available since 2002 and constantly upgraded, all methods are documented and its algorithms are published in peer-reviewed journals. When the confidence interval around a conservation grade is too wide, ConSurf assigns that residue a yellow color for "insufficient data". | The [http://consurf.tau.ac.il ConSurf Server], a project led by Nir Ben-Tal and Tal Pupko (Tel-Aviv University, Israel), colors each amino acid in a protein structure by its level of evolutionary conservation. Functional sites are marked by clusters of '''con'''served '''surf'''ace residues. Available since 2002 and constantly upgraded, all methods are documented and its algorithms are published in peer-reviewed journals. When the confidence interval around a conservation grade is too wide, ConSurf assigns that residue a yellow color for "insufficient data". | ||
For some quick examples, see [[Introduction to Evolutionary Conservation]]. | |||
Here are listed pages in Proteopedia about evolutionary conservation, how to use the [http://consurf.tau.ac.il ConSurf Server], and how to interpret its results to identify functional sites in proteins. | Here are listed pages in Proteopedia about evolutionary conservation, how to use the [http://consurf.tau.ac.il ConSurf Server], and how to interpret its results to identify functional sites in proteins. | ||