2ciu: Difference between revisions
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<StructureSection load='2ciu' size='340' side='right'caption='[[2ciu]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='2ciu' size='340' side='right'caption='[[2ciu]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ciu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2ciu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CIU FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ciu OCA], [https://pdbe.org/2ciu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ciu RCSB], [https://www.ebi.ac.uk/pdbsum/2ciu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ciu ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ciu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ciu OCA], [https://pdbe.org/2ciu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ciu RCSB], [https://www.ebi.ac.uk/pdbsum/2ciu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ciu ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/TIM21_YEAST TIM21_YEAST] Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Required to keep the TOM and the TIM23 complexes in close contact. At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix. In the complex, it acts as an antagonist of TIM50 by reducing preprotein accumulation at the TOM23 complex and promotes dissociation of the PAM complex from the TIM23 complex.<ref>PMID:15797382</ref> <ref>PMID:15878866</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Albrecht | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Pfanner | [[Category: Albrecht R]] | ||
[[Category: Rehling | [[Category: Pfanner N]] | ||
[[Category: Zeth | [[Category: Rehling P]] | ||
[[Category: Zeth K]] | |||