Enkephalin: Difference between revisions
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< | ==Your Heading Here (maybe something like 'Structure')== | ||
<StructureSection load='5E3A' size='350' side='right' caption='Structure of human DPP3 in complex with opioid peptide leu-enkephalin' scene=''> | |||
== General function == | == General function == | ||
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Dual Enkephalinase Inhibitors (DENKIs) are a novel therapeutic approach for opioid use disorders. This class of compounds physiologically activates the endogenous opioid system by inhibiting the enzymes responsible for the breakdown of enkephalins, protecting endogenous enkephalins, increasing their half-lives and physiological actions <ref>Alvarez-Perez, B, Poras, H, Maldonado, R. THE INHIBITION OF ENKEPHALIN CATABOLISM BY DUAL ENKEPHALINASE INHIBITOR: A NOVEL POSSIBLE THERAPEUTIC APPROACH FOR OPIOID USE DISORDERS. Br J Pharmacol. 2021. Accepted Author Manuscript. https://doi.org/10.1111/bph.15656</ref>. | Dual Enkephalinase Inhibitors (DENKIs) are a novel therapeutic approach for opioid use disorders. This class of compounds physiologically activates the endogenous opioid system by inhibiting the enzymes responsible for the breakdown of enkephalins, protecting endogenous enkephalins, increasing their half-lives and physiological actions <ref>Alvarez-Perez, B, Poras, H, Maldonado, R. THE INHIBITION OF ENKEPHALIN CATABOLISM BY DUAL ENKEPHALINASE INHIBITOR: A NOVEL POSSIBLE THERAPEUTIC APPROACH FOR OPIOID USE DISORDERS. Br J Pharmacol. 2021. Accepted Author Manuscript. https://doi.org/10.1111/bph.15656</ref>. | ||
</StructureSection> | |||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
== References == | == References == | ||
<references/> | <references/> | ||