7vsl: Difference between revisions

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-'''Unreleased structure'''
-The entry 7vsl is ON HOLD  until Paper Publication
+==Crystal structure of PDE8A catalytic domain in complex with 10==
+<StructureSection load='7vsl' size='340' side='right'caption='[[7vsl]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-Authors: Wu, X.-N., Zhou, Q., Huang, Y.-D., Li, Z., Wu, Y., Luo, H.-B.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7vsl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VSL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VSL FirstGlance]. <br>
-Description: Crystal structure of PDE8A catalytic domain in complex with 10
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7XI:2-chloro-9-(3-(2,2-difluoroethoxy)benzyl)-9H-purin-6-amine'>7XI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vsl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vsl OCA], [https://pdbe.org/7vsl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vsl RCSB], [https://www.ebi.ac.uk/pdbsum/7vsl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vsl ProSAT]</span></td></tr>
-[[Category: Wu, X.-N]]
+</table>
-[[Category: Luo, H.-B]]
+== Function ==
-[[Category: Huang, Y.-D]]
+[https://www.uniprot.org/uniprot/PDE8A_HUMAN PDE8A_HUMAN] Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.<ref>PMID:18983167</ref>
-[[Category: Li, Z]]
+== References ==
-[[Category: Zhou, Q]]
+<references/>
-[[Category: Wu, Y]]
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Huang Y-D]]
+[[Category: Li Z]]
+[[Category: Luo H-B]]
+[[Category: Wu X-N]]
+[[Category: Wu Y]]
+[[Category: Zhou Q]]