2zc6: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zc6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZC6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zc6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZC6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TEB:(4R,5S)-3-(1-(4,5-DIHYDROTHIAZOL-2-YL)AZETIDIN-3-YLTHIO)-5-((2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL)-4-METHYL-4,5-+DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>TEB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zc3|2zc3]], [[2zc4|2zc4]], [[2zc5|2zc5]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TEB:(4R,5S)-3-(1-(4,5-DIHYDROTHIAZOL-2-YL)AZETIDIN-3-YLTHIO)-5-((2S,3R)-3-HYDROXY-1-OXOBUTAN-2-YL)-4-METHYL-4,5-+DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>TEB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pbpA, exp2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 Streptococcus pneumoniae]), pbp1a ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 Streptococcus pneumoniae])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc6 OCA], [https://pdbe.org/2zc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zc6 RCSB], [https://www.ebi.ac.uk/pdbsum/2zc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zc6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc6 OCA], [https://pdbe.org/2zc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zc6 RCSB], [https://www.ebi.ac.uk/pdbsum/2zc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zc6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PBPA_STRR6 PBPA_STRR6]] Cell wall formation.  
[https://www.uniprot.org/uniprot/PBPA_STRPN PBPA_STRPN] Cell wall formation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
[[Category: Takeuchi, Y]]
[[Category: Takeuchi Y]]
[[Category: Watanabe, T]]
[[Category: Watanabe T]]
[[Category: Yamada, M]]
[[Category: Yamada M]]
[[Category: Antibiotic]]
[[Category: Antibiotic resistance]]
[[Category: Biosynthetic protein]]
[[Category: Cell shape]]
[[Category: Cell wall]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Multifunctional enzyme]]
[[Category: Penicillin-binding]]
[[Category: Peptidoglycan synthesis]]
[[Category: Secreted]]
[[Category: Tebipenem]]

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