HypA-HypB-HypC-HypD-HypE-HypF: Difference between revisions
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<StructureSection load='2z1d' size='340' side='right' caption='HypD with Fe4S4 center (PDB code [[2z1d]])' scene=''> | <StructureSection load='2z1d' size='340' side='right' caption='HypD with Fe4S4 center (PDB code [[2z1d]])' scene=''> | ||
== Function == | == Function == | ||
The [NiFe] hydrogenase or '''hydrogenase expression/formation protein''' contains a NiFe(CO)(CN)2 in its reaction center. '''HypA, HypB, HypC, HypD, HypE and HypF''' are required for the maturation of [NiFe] hydrogenase. '''HypA'''<ref>PMID:15995183</ref> and '''HypB'''<ref>PMID:9140970</ref> are involved in the insertion of Ni atom. '''HypE''' and '''HypF'''<ref>PMID:15291820</ref> catalyze the biosynthesis of the CN ligand. '''HypC''' and '''HypD'''<ref>PMID:15504408</ref> deliver the Fe and CO to the hydrogenase active center. | The [NiFe] hydrogenase or '''hydrogenase expression/formation protein''' contains a NiFe(CO)(CN)2 in its reaction center. '''HypA, HypB, HypC, HypD, HypE and HypF''' are required for the maturation of [NiFe] hydrogenase. | ||
*'''HypA'''<ref>PMID:15995183</ref> and '''HypB'''<ref>PMID:9140970</ref> are involved in the insertion of Ni atom. For more details of HypA see [[Molecular Playground/HypA]]. | |||
*'''HypE''' and '''HypF'''<ref>PMID:15291820</ref> catalyze the biosynthesis of the CN ligand. ' | |||
*''HypC''' and '''HypD'''<ref>PMID:15504408</ref> deliver the Fe and CO to the hydrogenase active center. | |||
== 3D Structures of HypA, HypB, HypC, HypD, HypE and HypF == | == 3D Structures of HypA, HypB, HypC, HypD, HypE and HypF == |