AlphaFold: Difference between revisions
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:: AlphaFold 2 can often predict the correct homo-oligomer structure when given the correct oligomeric state (number of copies in complex); however, it's not always able to predict the correct oligomeric state ''a priori''. | :: AlphaFold 2 can often predict the correct homo-oligomer structure when given the correct oligomeric state (number of copies in complex); however, it's not always able to predict the correct oligomeric state ''a priori''. | ||
:: "AF2 models can be used across diverse applications equally well compared to experimentally determined structures, when the confidence metrics are critically considered." | :: "AF2 models can be used across diverse applications equally well compared to experimentally determined structures, when the confidence metrics are critically considered." | ||
* '''Protein complex prediction with AlphaFold-Multimer ''' | |||
: Evans et al., 2021 | |||
: https://www.biorxiv.org/content/10.1101/2021.10.04.463034 | |||
: Highlights: | |||
:: Fine tuned Alphafold 2 model for protein interaction predictions. | |||
:: "The source code and weights for the trained models will be made available shortly." | |||