Lipase lid morph: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
Line 16: | Line 16: | ||
*<scene name='Lipase_lid_morph/Lightseagreen_hinge/5'>Spacefilling morph</scene> ({{Template:ColorKey_Polar}}, {{Template:ColorKey_Hydrophobic}}, <font color='orange'><b>catalytic triad: Ser209, Glu341, and His449</b></font><ref name='2states1994' />). | *<scene name='Lipase_lid_morph/Lightseagreen_hinge/5'>Spacefilling morph</scene> ({{Template:ColorKey_Polar}}, {{Template:ColorKey_Hydrophobic}}, <font color='orange'><b>catalytic triad: Ser209, Glu341, and His449</b></font><ref name='2states1994' />). | ||
An alternate morph<ref>This is a [[Jmol/Storymorph|rigid body morph]] based on the superoposition in PDB file is [[Image:1TRH_1LPM.pdb]].</ref> shows a <scene name='49/493694/Storymorph/1'>different path</scene> between the same initial and final experimental structures. The position of the inhibitor in the 1lpm structure is shown throughout; it would clash with the conformation of the lid in the 1trh structures, showing that closed lid and inhibitor binding are mutually exclusive. | |||
<jmol> | |||
<jmolButton> | |||
<script>script "https://proteopedia.org/wiki/images/a/a2/Storymorph.spt"; | |||
domain2 = {(75-85)}; | |||
model 2; | |||
structures = [{1.2}, {1.1}]; | |||
domains = [ | |||
[{protein and not domain2}], | |||
[{domain2}, {(74,86) and *.CA}], | |||
]; | |||
morph_palindrome = 1; | |||
morph(15,structures,domains);</script> | |||
<text>Run alternate morph</text> | |||
</jmolButton> | |||
</jmol> | |||
==See Also== | ==See Also== |