1j2g: Difference between revisions
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<StructureSection load='1j2g' size='340' side='right'caption='[[1j2g]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='1j2g' size='340' side='right'caption='[[1j2g]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1j2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1j2g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._TB-90 Bacillus sp. TB-90]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J2G FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZA:8-AZAXANTHINE'>AZA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j2g OCA], [https://pdbe.org/1j2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j2g RCSB], [https://www.ebi.ac.uk/pdbsum/1j2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j2g ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j2g OCA], [https://pdbe.org/1j2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j2g RCSB], [https://www.ebi.ac.uk/pdbsum/1j2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j2g ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PUCL_BACSB PUCL_BACSB] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 23: | Line 22: | ||
==See Also== | ==See Also== | ||
*[[Urate | *[[Urate oxidase 3D structures|Urate oxidase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Bacillus sp. TB-90]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hibi | [[Category: Hibi T]] | ||
[[Category: Nago | [[Category: Nago T]] | ||
[[Category: Nishiya | [[Category: Nishiya Y]] | ||
[[Category: Oda | [[Category: Oda J]] | ||
Latest revision as of 02:41, 28 December 2023
Crystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-AzaxanthineCrystal structure of Urate oxidase from Bacillus SP. TB-90 co-crystallized with 8-Azaxanthine
Structural highlights
FunctionPUCL_BACSB Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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