10mh: Difference between revisions
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<StructureSection load='10mh' size='340' side='right'caption='[[10mh]], [[Resolution|resolution]] 2.55Å' scene=''> | <StructureSection load='10mh' size='340' side='right'caption='[[10mh]], [[Resolution|resolution]] 2.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[10mh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[10mh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10MH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10MH FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene>, <scene name='pdbligand=5NC:5-AZA-CYTIDINE-5MONOPHOSPHATE'>5NC</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10mh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10mh OCA], [https://pdbe.org/10mh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10mh RCSB], [https://www.ebi.ac.uk/pdbsum/10mh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10mh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10mh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10mh OCA], [https://pdbe.org/10mh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10mh RCSB], [https://www.ebi.ac.uk/pdbsum/10mh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10mh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Haemophilus haemolyticus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Alvarez | [[Category: Alvarez E]] | ||
[[Category: Brank | [[Category: Brank A]] | ||
[[Category: Cheng | [[Category: Cheng X]] | ||
[[Category: Christman | [[Category: Christman JK]] | ||
[[Category: | [[Category: Ford Junior H]] | ||
[[Category: Goddard | [[Category: Goddard A]] | ||
[[Category: | [[Category: Marasco CJ]] | ||
[[Category: | [[Category: Marquez VE]] | ||
[[Category: | [[Category: O'Gara M]] | ||
[[Category: Sheikhnejad | [[Category: Sheikhnejad G]] | ||
[[Category: Sufrin | [[Category: Sufrin JR]] | ||