Protein crosslinks: Difference between revisions

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====Lysine-Cysteine NOS Crosslinks====
====Lysine-Cysteine NOS Crosslinks====
*[[Lysine-cysteine NOS bonds]] as protein crosslinks were first reported in 2021 by Wensien ''et al.''<ref name="wensien2021">PMID: 33953398</ref>. They reported that following a search of the entire PDB, they "identified a number of proteins from all domains of life that are highly likely to possess one or more NOS bridges", to be detailed in a manuscript in preparation. However, because such bonds were not recognized before 2021, those that occur in previously published structures would have been overlooked.
See [[Lysine-cysteine NOS bonds]] for a detailed description and examples. These were first reported in 2021 by Wensien ''et al.''<ref name="wensien2021">PMID: 33953398</ref>. They reported that following a search of the entire PDB, they "identified a number of proteins from all domains of life that are highly likely to possess one or more NOS bridges", to be detailed in a manuscript in preparation. However, because such bonds were not recognized before 2021, those that occur in previously published structures would have been overlooked.


*Example: [[6zx4]] was analyzed in depth and provided the first documented case. Additional examples will be found in the lower left panel of FirstGlance when this example is viewed.
*Example: [[6zx4]] was analyzed in depth and provided the first documented case. Additional examples will be found in the lower left panel of FirstGlance when this example is viewed.

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Eric Martz