Thioether protein crosslinks: Difference between revisions
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Thioether bonds between the sidechains of '''cysteine and tyrosine''' have been well studied in cysteine dioxygenases<ref>PMID:25390690</ref>. | Thioether bonds between the sidechains of '''cysteine and tyrosine''' have been well studied in cysteine dioxygenases<ref>PMID:25390690</ref>, and observed in catalase and galactose oxidase (see examples below). | ||
Thioether bonds between cysteine and ligands are common, but are generally not crosslinks between polypeptides. Thioether bonds between '''cysteine and the vinyl groups of hemes''' are common. Diverse other '''ligands''' are bonded to protein via cysteine thioether linkages. | Thioether bonds between cysteine and ligands are common, but are generally not crosslinks between polypeptides. Thioether bonds between '''cysteine and the vinyl groups of hemes''' are common. Diverse other '''ligands''' are bonded to protein via cysteine thioether linkages. |