2r4s: Difference between revisions
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<StructureSection load='2r4s' size='340' side='right'caption='[[2r4s]], [[Resolution|resolution]] 3.40Å' scene=''> | <StructureSection load='2r4s' size='340' side='right'caption='[[2r4s]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2r4s]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2r4s]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R4S FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r4s OCA], [https://pdbe.org/2r4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r4s RCSB], [https://www.ebi.ac.uk/pdbsum/2r4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r4s ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r4s OCA], [https://pdbe.org/2r4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r4s RCSB], [https://www.ebi.ac.uk/pdbsum/2r4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r4s ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ADRB2_HUMAN ADRB2_HUMAN] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Burghammer | [[Category: Burghammer M]] | ||
[[Category: Choi | [[Category: Choi HJ]] | ||
[[Category: Edwards | [[Category: Edwards PC]] | ||
[[Category: Fischetti | [[Category: Fischetti RF]] | ||
[[Category: Kobilka | [[Category: Kobilka BK]] | ||
[[Category: Kobilka | [[Category: Kobilka TS]] | ||
[[Category: Rasmussen | [[Category: Rasmussen SGF]] | ||
[[Category: Ratnala | [[Category: Ratnala VR]] | ||
[[Category: Rosenbaum | [[Category: Rosenbaum DM]] | ||
[[Category: Sanishvili | [[Category: Sanishvili R]] | ||
[[Category: Schertler | [[Category: Schertler GF]] | ||
[[Category: Thian | [[Category: Thian FS]] | ||
[[Category: Weis | [[Category: Weis WI]] | ||