2ohc: Difference between revisions

No edit summary
No edit summary
Line 3: Line 3:
<StructureSection load='2ohc' size='340' side='right'caption='[[2ohc]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2ohc' size='340' side='right'caption='[[2ohc]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ohc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Theac Theac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OHC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ohc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum_DSM_1728 Thermoplasma acidophilum DSM 1728]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OHC FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ohe|2ohe]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">endA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=273075 THEAC])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/tRNA-intron_endonuclease tRNA-intron endonuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.9 3.1.27.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ohc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ohc OCA], [https://pdbe.org/2ohc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ohc RCSB], [https://www.ebi.ac.uk/pdbsum/2ohc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ohc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ohc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ohc OCA], [https://pdbe.org/2ohc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ohc RCSB], [https://www.ebi.ac.uk/pdbsum/2ohc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ohc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ENDA_THEAC ENDA_THEAC]] Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).  
[https://www.uniprot.org/uniprot/ENDA_THEAC ENDA_THEAC] Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 38: Line 36:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Theac]]
[[Category: Thermoplasma acidophilum DSM 1728]]
[[Category: TRNA-intron endonuclease]]
[[Category: Hwang KY]]
[[Category: Hwang, K Y]]
[[Category: Kim YK]]
[[Category: Kim, Y K]]
[[Category: Lee WH]]
[[Category: Lee, W H]]
[[Category: Mizutani K]]
[[Category: Mizutani, K]]
[[Category: Park SY]]
[[Category: Park, S Y]]
[[Category: Rhee KH]]
[[Category: Rhee, K H]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Intron]]
[[Category: Splicing]]
[[Category: Trna]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA