2mxc: Difference between revisions

<StructureSection load='2mxc' size='340' side='right'caption='[[2mxc]]' scene=''>

<table><tr><td colspan='2'>[[2mxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MXC FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxc OCA], [https://pdbe.org/2mxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mxc RCSB], [https://www.ebi.ac.uk/pdbsum/2mxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mxc ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SNX3_HUMAN SNX3_HUMAN] MMEP syndrome. The gene represented in this entry may be involved in disease pathogenesis. A chromosomal aberration involving SNX3 has been found in patients with syndromic microphthalmia. Translocation t(6;13)(q21;q12).

[https://www.uniprot.org/uniprot/SNX3_HUMAN SNX3_HUMAN] Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Plays a role in protein transport between cellular compartments. Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G (By similarity). Not involved in EGFR degradation.<ref>PMID:11433298</ref> <ref>PMID:18767904</ref>  

[[Category: Homo sapiens]]

[[Category: Gruenberg JJG]]

[[Category: Kaur JJK]]

[[Category: Lenoir MML]]

[[Category: Overduin MMO]]

[[Category: Rajesh SSR]]