2mwn: Difference between revisions

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==Talin-F3 / RIAM N-terminal Peptide complex==
==Talin-F3 / RIAM N-terminal Peptide complex==
<StructureSection load='2mwn' size='340' side='right'caption='[[2mwn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2mwn' size='340' side='right'caption='[[2mwn]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mwn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MWN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mwn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MWN FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TLN1, KIAA1027, TLN ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mwn OCA], [https://pdbe.org/2mwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mwn RCSB], [https://www.ebi.ac.uk/pdbsum/2mwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mwn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mwn OCA], [https://pdbe.org/2mwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mwn RCSB], [https://www.ebi.ac.uk/pdbsum/2mwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mwn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/AB1IP_HUMAN AB1IP_HUMAN]] Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.<ref>PMID:14530287</ref> <ref>PMID:15469846</ref> [[https://www.uniprot.org/uniprot/TLN1_HUMAN TLN1_HUMAN]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity).
[https://www.uniprot.org/uniprot/AB1IP_HUMAN AB1IP_HUMAN] Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.<ref>PMID:14530287</ref> <ref>PMID:15469846</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Byzova, T]]
[[Category: Byzova T]]
[[Category: Dwivedi, P]]
[[Category: Dwivedi P]]
[[Category: Fukuda, K]]
[[Category: Fukuda K]]
[[Category: Hirbawi, J]]
[[Category: Hirbawi J]]
[[Category: Liu, J]]
[[Category: Liu J]]
[[Category: Plow, E F]]
[[Category: Plow EF]]
[[Category: Qin, J]]
[[Category: Qin J]]
[[Category: Wu, J]]
[[Category: Wu J]]
[[Category: Yang, J]]
[[Category: Yang J]]
[[Category: Zhang, H]]
[[Category: Zhang H]]
[[Category: Zhu, L]]
[[Category: Zhu L]]
[[Category: Integrin]]
[[Category: Riam]]
[[Category: Structural protein-signaling protein complex]]
[[Category: Talin]]

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OCA