2mm8: Difference between revisions

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==Structural and biochemical characterization of Jaburetox==
==Structural and biochemical characterization of Jaburetox==
<StructureSection load='2mm8' size='340' side='right'caption='[[2mm8]], [[NMR_Ensembles_of_Models | 5 NMR models]]' scene=''>
<StructureSection load='2mm8' size='340' side='right'caption='[[2mm8]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canen Canen]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MM8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MM8 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">JBURE-II ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3823 CANEN])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mm8 OCA], [https://pdbe.org/2mm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2mm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mm8 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Urease Urease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.5 3.5.1.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mm8 OCA], [https://pdbe.org/2mm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2mm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mm8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UREA2_CANEN UREA2_CANEN] Urea hydrolase involved in recycling metabolically derived urea generated internally or externally (By similarity). Is able to impair growth of the phytopathogenic fungus Penicillium herguei, and shows entomotoxic activity by inhibiting diuresis in Malpighian tubules isolated from Rhodnius prolixus (PubMed:21893219).[UniProtKB:P07374]<ref>PMID:21893219</ref>


==See Also==
==See Also==
*[[Urease 3D structures|Urease 3D structures]]
*[[Urease 3D structures|Urease 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Canen]]
[[Category: Canavalia ensiformis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Urease]]
[[Category: Carlini C]]
[[Category: Carlini, C]]
[[Category: Ciurli S]]
[[Category: Ciurli, S]]
[[Category: Dobrovolska O]]
[[Category: Dobrovolska, O]]
[[Category: Lopez F]]
[[Category: Lopez, F]]
[[Category: Zambelli B]]
[[Category: Zambelli, B]]
[[Category: Disordered protein]]
[[Category: Hydrolase]]

Revision as of 11:01, 8 March 2023

Structural and biochemical characterization of JaburetoxStructural and biochemical characterization of Jaburetox

Structural highlights

2mm8 is a 1 chain structure with sequence from Canavalia ensiformis. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

UREA2_CANEN Urea hydrolase involved in recycling metabolically derived urea generated internally or externally (By similarity). Is able to impair growth of the phytopathogenic fungus Penicillium herguei, and shows entomotoxic activity by inhibiting diuresis in Malpighian tubules isolated from Rhodnius prolixus (PubMed:21893219).[UniProtKB:P07374][1]

See Also

References

  1. ↑ Mulinari F, Becker-Ritt AB, Demartini DR, Ligabue-Braun R, Stanisçuaski F, Verli H, Fragoso RR, Schroeder EK, Carlini CR, Grossi-de-Sá MF. Characterization of JBURE-IIb isoform of Canavalia ensiformis (L.) DC urease. Biochim Biophys Acta. 2011 Dec;1814(12):1758-68. PMID:21893219 doi:10.1016/j.bbapap.2011.07.022
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