Beta-lactamase 3D structures: Difference between revisions

Joel L. Sussman (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 7: Line 7:


**[[3dtm]], [[1bza]], [[1ck3]], [[1esu]], [[1jwp]], [[1lhy]], [[1li0]], [[1m40]], [[1zg6]], [[2v1z]], [[2v20]], [[3cmz]], [[3jyi]], [[4ibr]], [[4ibx]], [[4mez]], [[4rx2]], [[4rx3]], [[6b2n]], [[5kpu]], [[5iq8]], [[5i63]], [[5i52]], [[5hw5]], [[5hw1]], [[5hvi]], [[6ayk]], [[6apa]] - EcBlac A Tem-1 (mutant)  - ''Escherichia coli''<br />
**[[3dtm]], [[1bza]], [[1ck3]], [[1esu]], [[1jwp]], [[1lhy]], [[1li0]], [[1m40]], [[1zg6]], [[2v1z]], [[2v20]], [[3cmz]], [[3jyi]], [[4ibr]], [[4ibx]], [[4mez]], [[4rx2]], [[4rx3]], [[6b2n]], [[5kpu]], [[5iq8]], [[5i63]], [[5i52]], [[5hw5]], [[5hw1]], [[5hvi]], [[6ayk]], [[6apa]] - EcBlac A Tem-1 (mutant)  - ''Escherichia coli''<br />
**[[1btl]], [[1iys]], [[1xpb]], [[1zg4]], [[4gku]], [[4rva]], [[5npo]] - EcBlac A Tem-1<br />
**[[1btl]], [[1iys]], [[1xpb]], [[1zg4]], [[4gku]], [[4rva]], [[5npo]], [[7u6q]] - EcBlac A Tem-1<br />
**[[4r4s]], [[4r4r]], [[4qy6]], [[4qy5]] - EcBlac A Tem-1/PSE-4<br />
**[[4r4s]], [[4r4r]], [[4qy6]], [[4qy5]] - EcBlac A Tem-1/PSE-4<br />
**[[1lhy]] - EcBlac A Tem-30 (mutant) <br />
**[[1lhy]] - EcBlac A Tem-30 (mutant) <br />
Line 14: Line 14:
**[[1yt4]] - EcBlac A Tem-76 (mutant) <br />
**[[1yt4]] - EcBlac A Tem-76 (mutant) <br />
**[[3toi]] - EcBlac A Tem-116 (mutant)<br />
**[[3toi]] - EcBlac A Tem-116 (mutant)<br />
**[[7qor]] – EcBlac Tem-171 <br />
**[[5chu]], [[5cgs]] – EcBlac FOX-4<br />
**[[5chu]], [[5cgs]] – EcBlac FOX-4<br />
**[[5cgw]] – EcBlac FOX-4 (mutant)<br />
**[[5cgw]] – EcBlac FOX-4 (mutant)<br />
**[[4zj2]], [[4zj1]] – EcBlac Tem (mutant) <br />
**[[4zj2]], [[4zj1]] – EcBlac Tem (mutant) <br />
**[[4id4]] – EcBlac/PaBlac Tem<br />
**[[4id4]] – EcBlac/PaBlac Tem<br />
**[[3o3v]] – EcBlac peptidase domain<br />
**[[1o7e]], [[1n4o]], [[5ne2]] – StmBlac A – ''Stenotrophonas maltophilia''<br />
**[[1o7e]], [[1n4o]], [[5ne2]] – StmBlac A – ''Stenotrophonas maltophilia''<br />
**[[1htz]] – KpBlac A Tem-52 – ''Klebsiella pneumoniae''<br />
**[[1htz]] – KpBlac A Tem-52 – ''Klebsiella pneumoniae''<br />
Line 57: Line 57:
**[[5fa7]] - EcBlac A + inhibitor<br />
**[[5fa7]] - EcBlac A + inhibitor<br />
**[[1nxy]], [[1ny0]], [[1nym]], [[1nyy]] - EcBlac A (mutant) + boronic acid inhibitor<br />
**[[1nxy]], [[1ny0]], [[1nym]], [[1nyy]] - EcBlac A (mutant) + boronic acid inhibitor<br />
**[[8de0]] - EcBlac A Tem-1 + drug<br />
**[[8de1]], [[8de2]] - EcBlac A Tem-1 (mutant) + drug<br />
**[[1pzo]], [[1pzp]] - EcBlac A Tem-1 (mutant) + inhibitor<br />
**[[1pzo]], [[1pzp]] - EcBlac A Tem-1 (mutant) + inhibitor<br />
**[[1erm]], [[1ero]], [[1erq]] – EcBlac A Tem-1 + boronic acid inhibitor<br />
**[[1erm]], [[1ero]], [[1erq]] – EcBlac A Tem-1 + boronic acid inhibitor<br />
Line 75: Line 77:
**[[6afn]], [[6afp]] - BtBlac A (mutant) + boronic acid inhibitor <br />
**[[6afn]], [[6afp]] - BtBlac A (mutant) + boronic acid inhibitor <br />
**[[5ne1]] - StmBlac A + boronic acid inhibitor <br />
**[[5ne1]] - StmBlac A + boronic acid inhibitor <br />
**[[6qw7]], [[6qw8]] - StmBlac A + inhibitor <br />
**[[6qw7]], [[6qw8]], [[7bj8]] - StmBlac A + inhibitor <br />
**[[6w2z]] - BsBlac A + inhibitor <br />
**[[6w2z]] - BsBlac A + inhibitor <br />
**[[6w33]] – BcBlac A (mutant) + inhibitor <br />
**[[6w33]] – BcBlac A (mutant) + inhibitor <br />
Line 81: Line 83:
*β-lactamase class A binary complex with antibiotics
*β-lactamase class A binary complex with antibiotics


**[[7qlp]], [[7qnk]] – EcBlac Tem-171 + antibiotic<br />
**[[1tem]], [[1bt5]], [[1fqg]], [[1iyo]], [[1iyp]], [[1iyq]], [[1jvj]], [[3q07]], [[3q1f]] - EcBlac A (mutant) + antibiotic<br />
**[[1tem]], [[1bt5]], [[1fqg]], [[1iyo]], [[1iyp]], [[1iyq]], [[1jvj]], [[3q07]], [[3q1f]] - EcBlac A (mutant) + antibiotic<br />
**[[5kmw]] - EcBlac A (mutant) + penicillin derivative<br />
**[[5kmw]] - EcBlac A (mutant) + penicillin derivative<br />
Line 116: Line 119:
**[[4ua6]], [[6d7h]] – EcESBL Ctx-M-14 <br />
**[[4ua6]], [[6d7h]] – EcESBL Ctx-M-14 <br />
**[[1ylt]], [[5vth]], [[5twd]], [[6cyn]], [[6cyk]], [[6d7i]], [[6v5e]], [[6v6g]], [[6v6p]], [[7k2x]] - EcBlac A Ctx-M-14 (mutant)<br />
**[[1ylt]], [[5vth]], [[5twd]], [[6cyn]], [[6cyk]], [[6d7i]], [[6v5e]], [[6v6g]], [[6v6p]], [[7k2x]] - EcBlac A Ctx-M-14 (mutant)<br />
**[[4hbt]] – EcESBL Ctx-M-15<br />
**[[4hbt]], [[7u57]] – EcESBL Ctx-M-15<br />
**[[1ylw]] - EcESBL Ctx-M-16<br />
**[[1ylw]] - EcESBL Ctx-M-16<br />
**[[1ylp]] - EcESBL Ctx-M-27 (mutant)<br />
**[[1ylp]] - EcESBL Ctx-M-27 (mutant)<br />
Line 130: Line 133:
**[[4pm8]] - KpBlac A Ctx-M-14 <br />
**[[4pm8]] - KpBlac A Ctx-M-14 <br />
**[[4pm6]], [[4pma]] - KpBlac A Ctx-M-14 (mutant) <br />
**[[4pm6]], [[4pma]] - KpBlac A Ctx-M-14 (mutant) <br />
**[[7bh3]], [[7bh4]], [[7bh5]], [[7bh6]], [[7bh7]] - KpBlac A Ctx-M-15 <br />
**[[7qqc]], [[7r3q]], [[7r3r]] - KpBlac A Ctx-M-15 (mutant)<br />
**[[2qpn]] – KpESBL A Ges-1<br />
**[[2qpn]] – KpESBL A Ges-1<br />
**[[6ts9]] - PaESBL A Ges-5<br />
**[[6ts9]] - PaESBL A Ges-5<br />
Line 141: Line 146:
**[[3g2y]], [[3g2z]], [[3g30]], [[3g31]], [[3g32]], [[3g34]], [[3g35]], [[4dds]], [[4ddy]], [[4de0]], [[4de1]], [[4de2]], [[4de3]], [[1yly]], [[1ym1]], [[1yms]] - EcBlac A Ctx-M-9 + inhibitor<br />
**[[3g2y]], [[3g2z]], [[3g30]], [[3g31]], [[3g32]], [[3g34]], [[3g35]], [[4dds]], [[4ddy]], [[4de0]], [[4de1]], [[4de2]], [[4de3]], [[1yly]], [[1ym1]], [[1yms]] - EcBlac A Ctx-M-9 + inhibitor<br />
**[[4len]] - EcESBL Ctx-M-9 (mutant) + inhibitor<br />
**[[4len]] - EcESBL Ctx-M-9 (mutant) + inhibitor<br />
**[[4uaa]], [[4ua7]], [[6md8]], [[6mia]], [[6mz1]], [[6mz2]], [[6ooe]], [[6oof]], [[6ooj]], [[6ook]] – EcESBL Ctx-M-14 + inhibitor<br />
**[[4uaa]], [[4ua7]], [[6md8]], [[6mia]], [[6mz1]], [[6mz2]], [[6ooe]], [[6oof]], [[6ooj]], [[6ook]], [[7s0v]] – EcESBL Ctx-M-14 + inhibitor<br />
**[[6bt6]], [[6v7h]], [[6v7t]], [[6v83]], [[6v8v]] – EcESBL Ctx-M-14 (mutant) + inhibitor<br />
**[[6bt6]], [[6v7h]], [[6v7t]], [[6v83]], [[6v8v]] – EcESBL Ctx-M-14 (mutant) + inhibitor<br />
**[[4ua9]], [[1ylz]] – EcESBL Ctx-M-14 + boronic acid inhibitor<br />
**[[4ua9]], [[1ylz]] – EcESBL Ctx-M-14 + boronic acid inhibitor<br />
Line 148: Line 153:
**[[7k2w]], [[7k2y]] – EcESBL Ctx-M-14 (mutant) + antibiotic<br />
**[[7k2w]], [[7k2y]] – EcESBL Ctx-M-14 (mutant) + antibiotic<br />
**[[4xxr]], [[5u53]], [[5tw6]], [[5twe]] - EcESBL Ctx-M-14 (mutant) + antibiotic<br />
**[[4xxr]], [[5u53]], [[5tw6]], [[5twe]] - EcESBL Ctx-M-14 (mutant) + antibiotic<br />
**[[4hbu]], [[6sp6]] – EcESBL Ctx-M-15 + inhibitor<br />
**[[4hbu]], [[6sp6]], [[7u49]] – EcESBL Ctx-M-15 + inhibitor<br />
**[[4xuz]] - KpBlac A Ctx-M-15 + boronic acid inhibitor<br />
**[[4xuz]], [[7ti0]] - KpBlac A Ctx-M-15 + boronic acid inhibitor<br />
**[[7u4b]] – EcESBL Ctx-M-15 + antibiotic<br />
**[[6bu3]] – EcESBL Ctx-M-27 + inhibitor<br />
**[[6bu3]] – EcESBL Ctx-M-27 + inhibitor<br />
**[[4x69]] – EcESBL Ctx-M-44 + inhibitor<br />
**[[4x69]] – EcESBL Ctx-M-44 + inhibitor<br />
Line 162: Line 168:
**[[6bpf]] – SeESBL Ctx-M-151 + inhibitor <br />
**[[6bpf]] – SeESBL Ctx-M-151 + inhibitor <br />
**[[6d3g]] – CfESBL Per-2 + inhibitor <br />
**[[6d3g]] – CfESBL Per-2 + inhibitor <br />
**[[7bds]] – KpESBL Ctx-M-15 + drug <br />
**[[7bdr]], [[7qq5]] – KpESBL Ctx-M-15 (mutant) + drug <br />


*Extended-spectrum β-lactamase class A binary complex with antibiotics
*Extended-spectrum β-lactamase class A binary complex with antibiotics
Line 170: Line 178:
**[[3hlw]], [[3huo]], [[3hvf]] - EcESBL Ctx-M-9 (mutant) + antibiotic<br />
**[[3hlw]], [[3huo]], [[3hvf]] - EcESBL Ctx-M-9 (mutant) + antibiotic<br />
**[[4xxr]], [[5u53]], [[5tw6]], [[5twe]], [[6cyu]], [[6cyq]]. [[6bt6]] - EcESBL Ctx-M-14 (mutant) + antibiotic<br />
**[[4xxr]], [[5u53]], [[5tw6]], [[5twe]], [[6cyu]], [[6cyq]]. [[6bt6]] - EcESBL Ctx-M-14 (mutant) + antibiotic<br />
**[[4pm9]] - KpBlac A Ctx-M-14 + antibiotic<br />
**[[4pm9]], [[7q11]] - KpBlac A Ctx-M-14 + antibiotic<br />
**[[4pm5]], [[4pm7]] - KpBlac A Ctx-M-14 (mutant) + antibiotic<br />
**[[4pm5]], [[4pm7]] - KpBlac A Ctx-M-14 (mutant) + antibiotic<br />
**[[4s2i]] - KpBlac A Ctx-M-15 + antibiotic<br />
**[[4s2i]] - KpBlac A Ctx-M-15 + antibiotic<br />
**[[5gwa]] – SmESBL Tla-3 + antibiotic<br />
**[[5gwa]], [[7o0o]] – SmESBL Tla-3 + antibiotic<br />


*β-lactamase class A complex with β-lactamase inhibitor protein (Blip)
*β-lactamase class A complex with β-lactamase inhibitor protein (Blip)
Line 198: Line 206:
**[[1l9y]] - FgBlac B (mutant) <br />
**[[1l9y]] - FgBlac B (mutant) <br />
**[[5n5g]] - PaBlac B Vim-1<br />
**[[5n5g]] - PaBlac B Vim-1<br />
**[[1ko2]], [[1ko3]], [[4bz3]], [[4nq2]], [[5yd7]] – PaBlac B Vim-2 - ''Pseudomonas aeruginosa''<br />
**[[1ko2]], [[1ko3]], [[4bz3]], [[4nq2]], [[5yd7]], [[7cjl]] – PaBlac B Vim-2 - ''Pseudomonas aeruginosa''<br />
**[[2whg]], [[2wrs]] - PaBlac B Vim-4<br />
**[[2whg]], [[2wrs]] - PaBlac B Vim-4<br />
**[[4d1t]] - PaBlac B Vim-7<br />
**[[4d1t]] - PaBlac B Vim-7<br />
Line 207: Line 215:
**[[4ax0]], [[4ax1]] - PaBlac B Aim-1 (mutant)<br />
**[[4ax0]], [[4ax1]] - PaBlac B Aim-1 (mutant)<br />
**[[2y87]], [[2y8a]], [[2y8b]] - PaBlac B Vim-7<br />
**[[2y87]], [[2y8a]], [[2y8b]] - PaBlac B Vim-7<br />
**[[2x02]] - PaBlac Oxa-10<br />
**[[2x02]], [[7b3r]], [[7b3s]], [[7b3u]] - PaBlac Oxa-10<br />
**[[2x01]] - PaBlac Oxa-10 (mutant)<br />
**[[2x01]] - PaBlac Oxa-10 (mutant)<br />
**[[4uam]], [[2fhx]], [[4bp0]], [[5nde]] - PaBlac Imp-1 <br />
**[[4uam]], [[2fhx]], [[4bp0]], [[5nde]] - PaBlac Imp-1 <br />
Line 213: Line 221:
**[[6r79]], [[6yi4]] - PaBlac Imp-13 <br />
**[[6r79]], [[6yi4]] - PaBlac Imp-13 <br />
**[[5b3r]] - PaBlac Imp-18 <br />
**[[5b3r]] - PaBlac Imp-18 <br />
**[[5ev6]], [[5y5b]] - SmBlac Imp-1 – ''Serratia marcescens''<br />
**[[5ev6]], [[5y5b]], [[7dtm]] - SmBlac Imp-1 – ''Serratia marcescens''<br />
**[[1wuo]], [[1wup]] - SmBlac Imp-1 (mutant) <br />
**[[1wuo]], [[1wup]], [[7dtn]] - SmBlac Imp-1 (mutant) <br />
**[[3vpe]] - SmBlac Smb-1<br />
**[[3vpe]] - SmBlac Smb-1<br />
**[[5fdh]] - SmBlac Oxa-405<br />
**[[5fdh]] - SmBlac Oxa-405<br />
Line 269: Line 277:
**[[5b1u]], [[5b15]], [[5aya]], [[5axo]] - SmBlac Smb-1 + antibiotic<br />
**[[5b1u]], [[5b15]], [[5aya]], [[5axo]] - SmBlac Smb-1 + antibiotic<br />
**[[4zej]] - PsBlac Dim-1 + antibiotic<br />
**[[4zej]] - PsBlac Dim-1 + antibiotic<br />
**[[2aio]] – StmBlac B + antibiotic<br />
**[[2aio]], [[7a63]] – StmBlac B + antibiotic<br />
**[[5zge]], [[4ey2]], [[4eyb]], [[4eyf]], [[4efl]], [[4hl1]], [[4hl2]], [[4eyl]], [[4hky]], [[4ram]], [[4raw]], [[4rbs]], [[4rl0]], [[4rl2]], [[5of2]], [[5o2e]], ]], [[5o2f]], [[6jkb]]  – KpBlac B Ndm-1+ antibiotic<br />
**[[5zge]], [[4ey2]], [[4eyb]], [[4eyf]], [[4efl]], [[4hl1]], [[4hl2]], [[4eyl]], [[4hky]], [[4ram]], [[4raw]], [[4rbs]], [[4rl0]], [[4rl2]], [[5of2]], [[5o2e]], ]], [[5o2f]], [[6jkb]]  – KpBlac B Ndm-1+ antibiotic<br />
**[[4rm5]] – KpBlac B Ndm-1 (mutant) + antibiotic<br />
**[[4rm5]] – KpBlac B Ndm-1 (mutant) + antibiotic<br />
Line 281: Line 289:
**[[1jt1]] – FgBlac + captopril <br />
**[[1jt1]] – FgBlac + captopril <br />
**[[1jje]], [[1jjt]], [[3lce]], [[3wxc]], [[4c1f]], [[4c1g]], [[5ndb]] - PaBlac B Imp-1+ inhibitor<br />
**[[1jje]], [[1jjt]], [[3lce]], [[3wxc]], [[4c1f]], [[4c1g]], [[5ndb]] - PaBlac B Imp-1+ inhibitor<br />
**[[5n5h]] - PaBlac B Vim-1 + inhibitor<br />
**[[5n5h]], [[7afy]], [[7ayj]] - PaBlac B Vim-1 + inhibitor<br />
**[[4c1d]], [[4c1e]], [[4pvo]], [[4pvt]], [[4ua4]], [[5lm6]], [[5le1]], [[5lch]], [[5lcf]], [[5lca]], [[5fqc]], [[5acx]], [[5acw]], [[5acv]], [[5acu]], [[5y6d]], [[5nhz]], [[5ni0]], [[5n4s]], [[5n4t]], [[5mxq]], [[5mxr]], [[5k48]], [[6hf5]], [[6ew3]], [[5y6e]], [[5o7n]], [[6dd0]], [[6dd1]], [[6j8r]], [[6kxo]], [[6kzn]], [[6sp7]], [[6v1p]], [[6zyn]], [[6zyo]], [[6zyp]] - PaBlac B Vim-2 + inhibitor<br />
**[[4c1d]], [[4c1e]], [[4pvo]], [[4pvt]], [[4ua4]], [[5lm6]], [[5le1]], [[5lch]], [[5lcf]], [[5lca]], [[5fqc]], [[5acx]], [[5acw]], [[5acv]], [[5acu]], [[5y6d]], [[5nhz]], [[5ni0]], [[5n4s]], [[5n4t]], [[5mxq]], [[5mxr]], [[5k48]], [[6hf5]], [[6ew3]], [[5y6e]], [[5o7n]], [[6dd0]], [[6dd1]], [[6j8r]], [[6kxo]], [[6kzn]], [[6sp7]], [[6v1p]], [[6zyn]], [[6zyo]], [[6zyp]], [[7afx]], [[7chv]], [[7du1]]. [[7dub]], [[7due]], [[7duy]], [[7duz]], [[7dv1]], [[7dyy]], [[7dz0]], [[7dz1]] - PaBlac B Vim-2 + inhibitor<br />
**[[6ibs]], [[6ibv]], [[6jn6]], [[6o5t]], [[6rpn]] - PaBlac B Vim-2 + boronic acid inhibitor<br />
**[[6ibs]], [[6ibv]], [[6jn6]], [[6o5t]], [[6rpn]] - PaBlac B Vim-2 + boronic acid inhibitor<br />
**[[7a60]] - PaBlac B Vim-2 + antibiotic<br />
**[[5n55]], [[5n58]] - PaBlac B Vim-5 + inhibitor<br />
**[[5n55]], [[5n58]] - PaBlac B Vim-5 + inhibitor<br />
**[[5mm9]] - PaBlac B Vim-17 + inhibitor<br />
**[[5mm9]] - PaBlac B Vim-17 + inhibitor<br />
Line 291: Line 300:
**[[6k4t]], [[6k4x]] - SmBlac Smb-1+ inhibitor<br />
**[[6k4t]], [[6k4x]] - SmBlac Smb-1+ inhibitor<br />
**[[2doo]] - SmBlac Imp-1+ fluorescent agent<br />
**[[2doo]] - SmBlac Imp-1+ fluorescent agent<br />
**[[2fu8]], [[2fu9]], [[2gfj]], [[2gfk]], [[2hb9]], [[2qdt]], [[5dpx]], [[5evk]], [[5evd]], [[5evb]], [[5hh6]], [[5hh5]] - StmBlac B L1 , [[6xbe]], [[6xbf]], [[6zyq]]+ inhibitor<br />
**[[2fu8]], [[2fu9]], [[2gfj]], [[2gfk]], [[2hb9]], [[2qdt]], [[5dpx]], [[5evk]], [[5evd]], [[5evb]], [[5hh6]], [[5hh5]], [[7afz]] - StmBlac B L1 , [[6xbe]], [[6xbf]], [[6zyq]]+ inhibitor<br />
**[[3iof]], [[1x8i]], [[3iog]]– AhBlac B (mutant) + inhibitor<br />
**[[3iof]], [[1x8i]], [[3iog]]– AhBlac B (mutant) + inhibitor<br />
**[[1x8g]], [[2gkl]], [[2qds]] – AhBlac B + inhibitor<br />  
**[[1x8g]], [[2gkl]], [[2qds]] – AhBlac B + inhibitor<br />  
Line 314: Line 323:
**[[1zkj]], [[5f1f]], [[5k1d]], [[5gsc]] – EaBlac C – ''Enterobacter aerogenes''<br />
**[[1zkj]], [[5f1f]], [[5k1d]], [[5gsc]] – EaBlac C – ''Enterobacter aerogenes''<br />
**[[2qz6]] – Blac C – ''Pseudomonas fluorescens''<br />
**[[2qz6]] – Blac C – ''Pseudomonas fluorescens''<br />
**[[7mqn]] – Blac C –'' Rhodobacter sphaeroides''<br />
**[[3w8k]], [[6k8x]], [[6m5p]] – KpBlac C<br />
**[[3w8k]], [[6k8x]], [[6m5p]] – KpBlac C<br />
**[[6m5h]], [[6m5q]] – KpBlac C (mutant)<br />
**[[6m5h]], [[6m5q]] – KpBlac C (mutant)<br />
Line 349: Line 359:
**[[1g6a]] – PaBlac Pse-4 (mutant) <br />
**[[1g6a]] – PaBlac Pse-4 (mutant) <br />
**[[1ko2]] – PaBlac Vim-2<br />
**[[1ko2]] – PaBlac Vim-2<br />
**[[7l5v]], [[7n1m]] - PaBlac D Oxa-935<br />
**[[1k38]] – Blac D – ''Salmonella typhimurium''<br />
**[[1k38]] – Blac D – ''Salmonella typhimurium''<br />
**[[1m6k]] – EcBlac D<br />
**[[1m6k]] – EcBlac D<br />
**[[3if6]], [[4s2p]] - KpBlac D Oxa-46<br />
**[[3if6]], [[4s2p]] - KpBlac D Oxa-46<br />
**[[3hbr]], [[6hoo]], [[7ass]] – KpBlac D Oxa-48<br />
**[[3hbr]], [[6hoo]], [[7ass]], [[7lxg]] – KpBlac D Oxa-48<br />
**[[6i5d]], [[6rj7]] - KpBlac D Oxa-48 (mutant)<br />
**[[6i5d]], [[6rj7]] - KpBlac D Oxa-48 (mutant)<br />
**[[6huh]] - KpBlac D Oxa-427<br />
**[[6huh]] - KpBlac D Oxa-427<br />
Line 370: Line 381:
**[[6n1n]] – Blac D – ''Sebaldella termitidis''<br />
**[[6n1n]] – Blac D – ''Sebaldella termitidis''<br />
**[[6ue2]] – Blac D – ''Peptoclostridium difficile''<br />
**[[6ue2]] – Blac D – ''Peptoclostridium difficile''<br />
**[[6wy4]] – CdBlac D – ''Clostridium difficile''<br />
**[[6wy4]], [[7rl8]] – CdBlac D – ''Clostridium difficile''<br />
**[[7rlr]] – CdBlac D (mutant) <br />
**[[6w5g]] – BaBlac D – ''Bacillus atrophaeus''<br />
**[[6w5g]] – BaBlac D – ''Bacillus atrophaeus''<br />
**[[6w5o]] – BaBlac D (mutant) <br />
**[[6w5o]] – BaBlac D (mutant) <br />
**[[7k3m]] – CpBlac D <br />


*β-lactamase class D binary complex
*β-lactamase class D binary complex
Line 380: Line 393:
**[[3isg]] – EcBlac D + inhibitor<br />
**[[3isg]] – EcBlac D + inhibitor<br />
**[[4s2m]] - EncBlac D Oxa-163+ inhibitor<br />
**[[4s2m]] - EncBlac D Oxa-163+ inhibitor<br />
**[[7khy]], [[7khz]] - EncBlac D Oxa-163 (mutant) + drug<br />
**[[3pae]], [[3pag]], [[4f94]] - AbBlac D (mutant) + inhibitor  <br />
**[[3pae]], [[3pag]], [[4f94]] - AbBlac D (mutant) + inhibitor  <br />
**[[3znt]], [[4y0u]], [[4y0t]] - AbBlac D + inhibitor<br />
**[[3znt]], [[4y0u]], [[4y0t]] - AbBlac D + inhibitor<br />
**[[6mpq]], [[6b22]] - AbBlac D Oxa-24 + inhibitor<br />
**[[6mpq]], [[6b22]] - AbBlac D Oxa-24 + inhibitor<br />
**[[5vfd]] - AbBlac D Oxa-24 (mutant) + inhibitor<br />
**[[5vfd]] - AbBlac D Oxa-24 (mutant) + inhibitor<br />
**[[5fat]], [[5fas]], [[5faq]], [[5fap]], [[5fao]], [[5dva]], [[5dtt]], [[5dts]], [[5dtk]], [[5qa4]], [[5qa5]], [[5qa6]], [[5qa7]], [[5qa8]], [[5qa9]], [[5qaa]], [[5qab]], [[5qac]], [[5qad]], [[5qae]], [[5qaf]], [[5qag]], [[5qah]], [[5qai]], [[5qaj]], [[5qak]], [[5qal]], [[5qam]], [[5qan]], [[5qao]], [[5qap]], [[5qaq]], [[5qar]], [[5qas]], [[5qat]], [[5qau]], [[5qav]], [[5qaw]], [[5qax]], [[5qay]], [[5qaz]], [[5qb0]], [[5qb1]], [[5qb2]], [[5qb3]], [[5qb4]], [[6uvk]], [[6v1o]] - KpBlac D Oxa-48 + inhibitor<br />
**[[5fat]], [[5fas]], [[5faq]], [[5fap]], [[5fao]], [[5dva]], [[5dtt]], [[5dts]], [[5dtk]], [[5qa4]], [[5qa5]], [[5qa6]], [[5qa7]], [[5qa8]], [[5qa9]], [[5qaa]], [[5qab]], [[5qac]], [[5qad]], [[5qae]], [[5qaf]], [[5qag]], [[5qah]], [[5qai]], [[5qaj]], [[5qak]], [[5qal]], [[5qam]], [[5qan]], [[5qao]], [[5qap]], [[5qaq]], [[5qar]], [[5qas]], [[5qat]], [[5qau]], [[5qav]], [[5qaw]], [[5qax]], [[5qay]], [[5qaz]], [[5qb0]], [[5qb1]], [[5qb2]], [[5qb3]], [[5qb4]], [[6uvk]], [[6v1o]], [[7ass]], [[7aux]], [[7aw5]], [[7jhq]], [[7k5v]], [[7l8o]], [[7r6z]]  - KpBlac D Oxa-48 + inhibitor<br />


*β-lactamase class D binary complex with antibiotics
*β-lactamase class D binary complex with antibiotics


**[[1k6r]], [[1k54]] - PaBlac D + antibiotic<br />
**[[1k6r]], [[1k54]], [[7l5t]] - PaBlac D + antibiotic<br />
**[[2wgi]], [[2wkh]] - PaBlac D (mutant) + antibiotic<br />
**[[2wgi]], [[2wkh]] - PaBlac D (mutant) + antibiotic<br />
**[[6n6x]], [[6n6y]], [[6n6v]], [[6n6u]] - AbBlac D Oxa-23 (mutant) + antibiotic<br />
**[[6n6x]], [[6n6y]], [[6n6v]], [[6n6u]] - AbBlac D Oxa-23 (mutant) + antibiotic<br />
**[[7rpg]], [[7rpe]], [[7rpf]] - AbBlac D Oxa-24 + antibiotic<br />
**[[7rp8]], [[7rp9]], [[7rpa]], [[7rpb]], [[7rpc]], [[7rpd]] - AbBlac D Oxa-24 (mutant) + antibiotic<br />
**[[4x56]] - AbBlac D Oxa-160 + antibiotic<br />
**[[4x56]] - AbBlac D Oxa-160 + antibiotic<br />
**[[4x53]] - AbBlac D Oxa-160 (mutant) + antibiotic<br />
**[[4x53]] - AbBlac D Oxa-160 (mutant) + antibiotic<br />
**[[4x55]] - AbBlac D Oxa-225 (mutant) + antibiotic<br />
**[[4x55]] - AbBlac D Oxa-225 (mutant) + antibiotic<br />
**[[4mll]] - KpBlac D Oxa-1 + antibiotic<br />
**[[4mll]] - KpBlac D Oxa-1 + antibiotic<br />
**[[4s2j]], [[4s2k]], [[4s2n]], [[4wmc]], [[6pqi]], [[6psg]], [[6pt1]], [[6pt5]], [[6ptu]] - KpBlac D Oxa-48 + antibiotic<br />
**[[4s2j]], [[4s2k]], [[4s2n]], [[4wmc]], [[6pqi]], [[6psg]], [[6pt1]], [[6pt5]], [[6ptu]], [[7kh9]], [[7khq]] - KpBlac D Oxa-48 + antibiotic<br />
**[[6pxx]], [[7kh9]] - KpBlac D Oxa-48 (mutant) + antibiotic<br />
**[[6pxx]], [[7kh9]] - KpBlac D Oxa-48 (mutant) + antibiotic<br />
**[[7khy]] - KpBlac D Oxa-163 + antibiotic<br />
**[[7khy]] - KpBlac D Oxa-163 + antibiotic<br />

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky