7kk7: Difference between revisions
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<StructureSection load='7kk7' size='340' side='right'caption='[[7kk7]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='7kk7' size='340' side='right'caption='[[7kk7]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7kk7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[7kk7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KK7 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kk7 OCA], [https://pdbe.org/7kk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kk7 RCSB], [https://www.ebi.ac.uk/pdbsum/7kk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kk7 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kk7 OCA], [https://pdbe.org/7kk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kk7 RCSB], [https://www.ebi.ac.uk/pdbsum/7kk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kk7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PKHA7_HUMAN PKHA7_HUMAN] Required for zonula adherens biogenesis and maintenance (PubMed:19041755). Acts via its interaction with CAMSAP3, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site (PubMed:19041755). Mediates docking of ADAM10 to zonula adherens through a PDZD11-dependent interaction with the ADAM10-binding protein TSPAN33 (PubMed:30463011).<ref>PMID:19041755</ref> <ref>PMID:30463011</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Aleshin | [[Category: Aleshin AE]] | ||
[[Category: Liddington | [[Category: Liddington RC]] | ||
[[Category: Marassi | [[Category: Marassi FM]] | ||