SARS-CoV-2 spike protein fusion transformation: Difference between revisions
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[[Image:Spike protein fusion mainchain morph from Proteopedia.Org.gif]] | [[Image:Spike protein fusion mainchain morph from Proteopedia.Org.gif]] | ||
===Alternate | ===Alternate Pathway for Transformation=== | ||
Given that a [[morph]] is intended to help you compare two structures and does | Given that a [[morph]] is intended to help you compare two structures and does not portray a realistic transition pathway, there are many pathways we can imagine. Below is another one that has structural elements swing away from the core structure in a hinge motion as they change conformation. Another choice in this morph is to have different timings for the distinct changes to be able to follow them one at a time. | ||
In the morph at full resolution, you can see a large cavity disappearing, the beta sheets acquiring an additional strand from a different subunit (subunits shown in green, blue and red tints), and changes in the core helix bundle along with the formation of the triple helix protrusion. | In the morph at full resolution, you can see a large cavity disappearing, the beta sheets acquiring an additional strand from a different subunit (subunits shown in green, blue and red tints), and changes in the core helix bundle along with the formation of the triple helix protrusion. |