1h7n: Difference between revisions

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<StructureSection load='1h7n' size='340' side='right'caption='[[1h7n]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='1h7n' size='340' side='right'caption='[[1h7n]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1h7n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H7N FirstGlance]. <br>
<table><tr><td colspan='2'>[[1h7n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H7N FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SHF:LAEVULINIC+ACID'>SHF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aw5|1aw5]], [[1qml|1qml]], [[1qnv|1qnv]], [[1ylv|1ylv]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SHF:LAEVULINIC+ACID'>SHF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Porphobilinogen_synthase Porphobilinogen synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.24 4.2.1.24] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7n OCA], [https://pdbe.org/1h7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h7n RCSB], [https://www.ebi.ac.uk/pdbsum/1h7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h7n ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7n OCA], [https://pdbe.org/1h7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h7n RCSB], [https://www.ebi.ac.uk/pdbsum/1h7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h7n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HEM2_YEAST HEM2_YEAST]] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.  
[https://www.uniprot.org/uniprot/HEM2_YEAST HEM2_YEAST] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Porphobilinogen synthase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Brindley, A A]]
[[Category: Brindley AA]]
[[Category: Cooper, J B]]
[[Category: Cooper JB]]
[[Category: Erskine, P T]]
[[Category: Erskine PT]]
[[Category: Newbold, R]]
[[Category: Newbold R]]
[[Category: Shoolingin-Jordan, P M]]
[[Category: Shoolingin-Jordan PM]]
[[Category: Warren, M J]]
[[Category: Warren MJ]]
[[Category: Wood, S P]]
[[Category: Wood SP]]
[[Category: Aldolase]]
[[Category: Dehydratase]]
[[Category: Lyase]]
[[Category: Tetrapyrrole synthesis]]
[[Category: Tim barrel]]

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