6yj0: Difference between revisions

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==Solution NMR structure of titin N2A region Ig domain I83==
==Solution NMR structure of titin N2A region Ig domain I83==
<StructureSection load='6yj0' size='340' side='right'caption='[[6yj0]], [[NMR_Ensembles_of_Models | 40 NMR models]]' scene=''>
<StructureSection load='6yj0' size='340' side='right'caption='[[6yj0]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6yj0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YJ0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6yj0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YJ0 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ttn ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yj0 OCA], [https://pdbe.org/6yj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yj0 RCSB], [https://www.ebi.ac.uk/pdbsum/6yj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yj0 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yj0 OCA], [https://pdbe.org/6yj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yj0 RCSB], [https://www.ebi.ac.uk/pdbsum/6yj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yj0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TITIN_MOUSE TITIN_MOUSE]] Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.[UniProtKB:Q8WZ42]<ref>PMID:16702235</ref> <ref>PMID:17261657</ref>
[https://www.uniprot.org/uniprot/TITIN_MOUSE TITIN_MOUSE] Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.[UniProtKB:Q8WZ42]<ref>PMID:16702235</ref> <ref>PMID:17261657</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6yj0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6yj0" style="background-color:#fffaf0;"></div>
==See Also==
*[[Titin 3D structures|Titin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Gage M]]
[[Category: Gage, M]]
[[Category: Pfuhl M]]
[[Category: Pfuhl, M]]
[[Category: Calcium binding actin binding muscle i-band]]
[[Category: Protein binding]]

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