1e96: Difference between revisions

Revision as of 00:20, 1 July 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1e96.png

Template:STRUCTURE 1e96

STRUCTURE OF THE RAC/P67PHOX COMPLEXSTRUCTURE OF THE RAC/P67PHOX COMPLEX

Template:ABSTRACT PUBMED 11090627

About this StructureAbout this Structure

1E96 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

Structure of the TPR domain of p67phox in complex with Rac.GTP., Lapouge K, Smith SJ, Walker PA, Gamblin SJ, Smerdon SJ, Rittinger K, Mol Cell. 2000 Oct;6(4):899-907. PMID:11090627

Page seeded by OCA on Tue Jul 1 00:20:56 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1e96.jpg|left|200px]]
+{{Seed}}
+[[Image:1e96.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1e96|  PDB=1e96  |  SCENE=  }}
-'''STRUCTURE OF THE RAC/P67PHOX COMPLEX'''
+===STRUCTURE OF THE RAC/P67PHOX COMPLEX===
-==Overview==
+<!--
-p67phox is an essential part of the NADPH oxidase, a multiprotein enzyme complex that produces superoxide ions in response to microbial infection. Binding of the small GTPase Rac to p67phox is a key step in the assembly of the active enzyme complex. The structure of Rac.GTP bound to the N-terminal TPR (tetratricopeptide repeat) domain of p67phox reveals a novel mode of Rho family/effector interaction and explains the basis of GTPase specificity. Complex formation is largely mediated by an insertion between two TPR motifs, suggesting an unsuspected versatility of TPR domains in target recognition and in their more general role as scaffolds for the assembly of multiprotein complexes.
+The line below this paragraph, {{ABSTRACT_PUBMED_11090627}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 11090627 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_11090627}}
 ==About this Structure==
@@ Line 33: / Line 37: @@
 [[Category: Signalling complex]]
 [[Category: Tpr motif]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 14:49:12 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 00:20:56 2008''