1jyd: Difference between revisions
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='1jyd' size='340' side='right'caption='[[1jyd]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='1jyd' size='340' side='right'caption='[[1jyd]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jyd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1jyd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JYD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JYD FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jyd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jyd OCA], [https://pdbe.org/1jyd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jyd RCSB], [https://www.ebi.ac.uk/pdbsum/1jyd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jyd ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jyd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jyd OCA], [https://pdbe.org/1jyd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jyd RCSB], [https://www.ebi.ac.uk/pdbsum/1jyd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jyd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
[https://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:[https://omim.org/entry/180250 180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium. | |||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 38: | Line 38: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Acharya | [[Category: Acharya KR]] | ||
[[Category: Brew | [[Category: Brew K]] | ||
[[Category: Chrysina | [[Category: Chrysina ED]] | ||
[[Category: Greene | [[Category: Greene LH]] | ||
[[Category: Irons | [[Category: Irons LI]] | ||
[[Category: Papageorgiou | [[Category: Papageorgiou AC]] | ||