2km2: Difference between revisions
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==Galectin-1 dimer== | ==Galectin-1 dimer== | ||
<StructureSection load='2km2' size='340' side='right'caption='[[2km2 | <StructureSection load='2km2' size='340' side='right'caption='[[2km2]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2km2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2km2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KM2 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2km2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2km2 OCA], [https://pdbe.org/2km2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2km2 RCSB], [https://www.ebi.ac.uk/pdbsum/2km2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2km2 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2km2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2km2 OCA], [https://pdbe.org/2km2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2km2 RCSB], [https://www.ebi.ac.uk/pdbsum/2km2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2km2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Baum | [[Category: Baum LG]] | ||
[[Category: Daragan | [[Category: Daragan VA]] | ||
[[Category: Ermakova | [[Category: Ermakova E]] | ||
[[Category: Mayo | [[Category: Mayo KH]] | ||
[[Category: Nesmelova | [[Category: Nesmelova IV]] | ||
[[Category: Pang | [[Category: Pang M]] | ||