2k8y: Difference between revisions

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==Solution NMR Structure of Cgi121 from Methanococcus jannaschii. Northeast Structural Genomics Consortium Target MJ0187==
==Solution NMR Structure of Cgi121 from Methanococcus jannaschii. Northeast Structural Genomics Consortium Target MJ0187==
<StructureSection load='2k8y' size='340' side='right'caption='[[2k8y]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2k8y' size='340' side='right'caption='[[2k8y]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k8y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K8Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[2k8y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K8Y FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zd0|1zd0]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0187 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k8y OCA], [https://pdbe.org/2k8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k8y RCSB], [https://www.ebi.ac.uk/pdbsum/2k8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k8y ProSAT], [https://www.topsan.org/Proteins/NESGC/2k8y TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k8y OCA], [https://pdbe.org/2k8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k8y RCSB], [https://www.ebi.ac.uk/pdbsum/2k8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k8y ProSAT], [https://www.topsan.org/Proteins/NESGC/2k8y TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CG121_METJA CG121_METJA]] Component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, a step in the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Cgi121 stimulates Bud32 kinase activity via an activation of Bud32 autophosphorylation.<ref>PMID:18951093</ref>
[https://www.uniprot.org/uniprot/CG121_METJA CG121_METJA] Component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, a step in the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Cgi121 stimulates Bud32 kinase activity via an activation of Bud32 autophosphorylation.<ref>PMID:18951093</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 43067]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Fares, C]]
[[Category: Arrowsmith C]]
[[Category: Montelione, G T]]
[[Category: Fares C]]
[[Category: Structural genomic]]
[[Category: Montelione GT]]
[[Category: Neculai, D]]
[[Category: Neculai D]]
[[Category: Rumpel, S]]
[[Category: Rumpel S]]
[[Category: Sicheri, F]]
[[Category: Sicheri F]]
[[Category: Component of the keops complex]]
[[Category: Nesg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Regulatory subunit of the bud32 kinase]]
[[Category: Unknown function]]

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