2jw5: Difference between revisions
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==Polymerase Lambda BRCT domain== | ==Polymerase Lambda BRCT domain== | ||
<StructureSection load='2jw5' size='340' side='right'caption='[[2jw5 | <StructureSection load='2jw5' size='340' side='right'caption='[[2jw5]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jw5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2jw5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JW5 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jw5 OCA], [https://pdbe.org/2jw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jw5 RCSB], [https://www.ebi.ac.uk/pdbsum/2jw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jw5 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jw5 OCA], [https://pdbe.org/2jw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jw5 RCSB], [https://www.ebi.ac.uk/pdbsum/2jw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jw5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/DPOLL_HUMAN DPOLL_HUMAN] Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.<ref>PMID:11457865</ref> <ref>PMID:15537631</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jw5 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jw5 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | |||
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: DeRose | [[Category: DeRose EF]] | ||
[[Category: London | [[Category: London RE]] | ||
[[Category: Moon | [[Category: Moon AF]] | ||
[[Category: Mueller | [[Category: Mueller GA]] | ||
[[Category: Pedersen | [[Category: Pedersen LC]] | ||