2iip: Difference between revisions
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<StructureSection load='2iip' size='340' side='right'caption='[[2iip]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='2iip' size='340' side='right'caption='[[2iip]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2iip]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2iip]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IIP FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iip OCA], [https://pdbe.org/2iip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iip RCSB], [https://www.ebi.ac.uk/pdbsum/2iip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iip ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iip OCA], [https://pdbe.org/2iip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iip RCSB], [https://www.ebi.ac.uk/pdbsum/2iip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iip ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/NNMT_HUMAN NNMT_HUMAN] Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | |||
[[Category: Arrowsmith | [[Category: Avvakumov GV]] | ||
[[Category: Avvakumov | [[Category: Bernstein G]] | ||
[[Category: Bernstein | [[Category: Bochkarev A]] | ||
[[Category: Bochkarev | [[Category: Edwards AM]] | ||
[[Category: Edwards | [[Category: Loppnau P]] | ||
[[Category: Loppnau | [[Category: Min J]] | ||
[[Category: Min | [[Category: Plotnikov AN]] | ||
[[Category: Plotnikov | [[Category: Sundstrom M]] | ||
[[Category: Tempel W]] | |||
[[Category: Sundstrom | [[Category: Wasney G]] | ||
[[Category: Tempel | [[Category: Weigelt J]] | ||
[[Category: Wasney | [[Category: Wu H]] | ||
[[Category: Weigelt | [[Category: Zeng H]] | ||
[[Category: Wu | |||
[[Category: Zeng | |||