2ihd: Difference between revisions
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<StructureSection load='2ihd' size='340' side='right'caption='[[2ihd]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2ihd' size='340' side='right'caption='[[2ihd]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ihd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2ihd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IHD FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ihd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ihd OCA], [https://pdbe.org/2ihd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ihd RCSB], [https://www.ebi.ac.uk/pdbsum/2ihd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ihd ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ihd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ihd OCA], [https://pdbe.org/2ihd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ihd RCSB], [https://www.ebi.ac.uk/pdbsum/2ihd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ihd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/RGS8_HUMAN RGS8_HUMAN] Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Preferentially binds to G(o)-alpha and G(i)-alpha-3 (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith C]] | ||
[[Category: Bhatia | [[Category: Bhatia C]] | ||
[[Category: Bray | [[Category: Bray J]] | ||
[[Category: Burgess | [[Category: Burgess N]] | ||
[[Category: Doyle DA]] | |||
[[Category: Doyle | [[Category: Edwards A]] | ||
[[Category: Edwards | [[Category: Elkins J]] | ||
[[Category: Elkins | [[Category: Gileadi C]] | ||
[[Category: Gileadi | [[Category: Gileadi O]] | ||
[[Category: Gileadi | [[Category: Papagrigoriou E]] | ||
[[Category: Papagrigoriou | [[Category: Salah E]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Salah | [[Category: Turnbull AP]] | ||
[[Category: Sundstrom | [[Category: Ugochukwu E]] | ||
[[Category: Turnbull | [[Category: Weigelt J]] | ||
[[Category: Ugochukwu | [[Category: Von Delft F]] | ||
[[Category: Weigelt | |||
[[Category: | |||