AlphaFold2 examples from CASP 14: Difference between revisions

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*[[5vfk]] chain A, Uncharacterized protein
*[[5vfk]] chain A, Uncharacterized protein
**length 146, aligned residues '''61, RMSD 7.8 Å''', Z=3.3, structural alignment 11 %id.
**length 146, aligned residues '''61, RMSD 7.8 Å''', Z=3.3, structural alignment 11 %id.
Liisa Holm<ref name="dali2020" /> stated (March, 2021): "T1037 has a homologous template in the PDB. The parent structure of T1037, phage RNA polymerase (6vr4, 2166 amino acids), is homologous to the RNAi polymerase from Neurospora crassa (2j7nA, 934 amino acids)
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The [https://fatcat.godziklab.org/ FATCAT Server] reported that in order to superpose 150 residues (37% of 404) of T1037 with the closest structure in the PDB, 3 twists at hinges were required, after which an RMSD of 3.1 Å was achieved. For a 200-residue superposition (50% of 404), the best results after 3 twists had an RMSD of 5.4 Å.
The [https://fatcat.godziklab.org/ FATCAT Server] reported that in order to superpose 150 residues (37% of 404) of T1037 with the closest structure in the PDB, 3 twists at hinges were required, after which an RMSD of 3.1 Å was achieved. For a 200-residue superposition (50% of 404), the best results after 3 twists had an RMSD of 5.4 Å.

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Eric Martz