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Angiotensin-Converting Enzyme 3D structures: Difference between revisions

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**[[2iul]], [[2iux]], [[3nxq]], [[4c2n]], [[4c2o]], [[4c2q]], [[4c2r]] – hANCE (mutant) <br />
**[[2iul]], [[2iux]], [[3nxq]], [[4c2n]], [[4c2o]], [[4c2q]], [[4c2r]] – hANCE (mutant) <br />
**[[2c6f]] – hANCE N domain<br />
**[[2c6f]] – hANCE N domain<br />
**[[2x8y]] – DmANCE – Drosophila melanogaster<br />
**[[7wa3]] – miANCE - mink<br />
**[[7c8k]] – baANCE – bat - Cryo EM<br />
**[[2x8y]] – DmANCE – ''Drosophila melanogaster''<br />
**[[6s1y]] – moANCE N domain - mosquito<br />
**[[6s1y]] – moANCE N domain - mosquito<br />


*Angiotensin Converting Enzyme N domain (1-641) complex
*Angiotensin Converting Enzyme N domain or RBD (1-641) complex
 
**[[6zpq]], [[6zpt]] - hANCE 1 (mutant) <br />
**[[2c6n]], [[1o86]], [[4c2p]], [[2ydm]], [[1uze]], [[1uzf]], [[6h5x]] - hANCE 1 + drug<br />
**[[7z6z]] - hANCE 1 (mutant) + drug<br />
**[[6en5]], [[6en6]], [[4bzr]], [[6tt4]] - hANCE 1 + inhibitor<br />
**[[7q24]], [[7q25]], [[7q26]], [[7q27]], [[7q29]]  - hANCE 1 + inhibitor<br />
**[[4bzs]], [[6tt3]] – hANCE 1 mutant) + inhibitor<br />
**[[6f9r]], [[6f9t]], [[6f9u]], [[6f9v]] - hANCE 1 + chronic heart failure drug<br />
**[[7e7e]] - hANCE 2 + antibody<br />
 
**[[7v61]] – hANCE 2 + Na-dependent neutral amino acid
transporter + 3E8 – Cryo EM<br />
**[[4bxk]], [[4ca5]], [[4ca7]], [[4ca8]], [[2xy9]], [[2xyd]] – hANCE 1 + phosphinic inhibitor<br />
**[[4ca6]], [[6tt1]] - hANCE 1 (mutant) + phosphinic inhibitor<br />
**[[4aph]] – hANCE 1 + angiotensin II<br />
**[[4apj]], [[6qs1]] – hANCE 1 + bradykinin-potentiating peptide B<br />
**[[1r42]], [[1r4l]] – hANCE 2 + disordered segment of collectrin homology domain<br />


**[[6zpq]], [[6zpt]] - hANCE (mutant) <br />
**[[2c6n]], [[1o86]], [[4c2p]], [[2ydm]], [[1uze]], [[1uzf]], [[6h5x]] - hANCE + anti-hypertensive drug<br />
**[[6en5]], [[6en6]], [[4bzr]], [[6tt4]] - hANCE + inhibitor<br />
**[[4bzs]], [[6tt3]] – hANCE (mutant) + inhibitor<br />
**[[6f9r]], [[6f9t]], [[6f9u]], [[6f9v]] - hANCE + chronic heart failure drug<br />
**[[3kbh]], [[3d0g]], [[3d0h]], [[3d0i]], [[2ajf]], [[3sci]], [[3scj]], [[3sck]], [[3scl]], [[6cs2]], [[6acg]], [[6acj]], [[6ack]], [[6lzg]], [[6m0j]], [[6vw1]] – hANCE 2 + spike glycoprotein<br />
**[[7a91]], [[7a92]], [[7a94]], [[7a95]], [7a96]], [[7a97]], [[7a98]], [[7bh9]], [[7ct5]], [[7df4]], [[7kj2]], [[7kj3]], [[7kj4]], [[7kmb]], [[7kms]], [[7kmz]], [[7knb]], [[7kne]], [[7knh]], [[7kni]], [[7l7f]] – hANCE 2 + SARS-Cov-2 spike glycoprotein – Cryo EM<br />
**[[7dmu]] – hANCE 2 (mutant) + SARS-Cov-2 spike glycoprotein <br />
**[[4bxk]], [[4ca5]], [[4ca7]], [[4ca8]], [[2xy9]], [[2xyd]] – hANCE + phosphinic inhibitor<br />
**[[4ca6]], [[6tt1]] - hANCE (mutant) + phosphinic inhibitor<br />
**[[4aph]] – hANCE + angiotensin II<br />
**[[4apj]], [[6qs1]] – hANCE + bradykinin-potentiating peptide B<br />
**[[1r42]], [[1r4l]] – hANCE + disordered segment of collectrin homology domain<br />
**[[7c8d]] – ANCE + SARS-Cov-2 spike glycoprotein – cat - Cryo EM<br />
**[[7c8k]] – baANCE – bat - Cryo EM<br />
**[[7c8j]] – baANCE + SARS-Cov-2 spike glycoprotein<br />
**[[2xhm]] – DmANCE+K inhibitor<br />
**[[2xhm]] – DmANCE+K inhibitor<br />
**[[2x8z]], [[2x90]], [[2x91]], [[2x92]], [[2x93]], [[2x94]], [[2x95]], [[2x96]], [[2x97]], [[1j36]], [[1j37]], [[1j38]], [[3zqz]] – DmANCE+anti-hypertensive drug<br />
**[[2x8z]], [[2x90]], [[2x91]], [[2x92]], [[2x93]], [[2x94]], [[2x95]], [[2x96]], [[2x97]], [[1j36]], [[1j37]], [[1j38]], [[3zqz]] – DmANCE+anti-hypertensive drug<br />
**[[4aa1]] – DmANCE + angiotensin II<br />
**[[4aa1]] – DmANCE 1 + angiotensin II<br />
**[[4aa2]], [[4asr]] – DmANCE + bradykinin-potentiating peptide B<br />
**[[4aa2]], [[4asr]] – DmANCE 1 + bradykinin-potentiating peptide B<br />
**[[4asq]] – DmANCE + bradykinin peptide<br />
**[[4asq]] – DmANCE 1 + bradykinin peptide<br />
**[[6s1z]] – moANCE + fosinoprilat<br />
**[[6s1z]] – moANCE 2 + drug<br />
 
*Angiotensin Converting Enzyme N domain or RBD (1-641) complex with spike glycoprotein
 
**[[3kbh]], [[3d0g]], [[3d0h]], [[3d0i]], [[2ajf]], [[3sci]], [[3scj]], [[3sck]], [[3scl]], [[6cs2]], [[6acg]], [[6acj]], [[6ack]], [[6lzg]], [[6m0j]], [[6vw1]], [[7drv]], [[7ekc]], [[7eke]], [[7ekf]], [[7ekg]], [[7ekh]], [[7lo4]], [[7p19]], [[7p8i]], [[7sn0]], [[7u0n]], [[76u]], [[7whh]], [[7xaz]] – hANCE 2 +spike glycoprotein<br />
**[[7dmu]], [[7efp]], [[7efr]] , [[7nxc]], [[7rpv]] – hANCE 2 (mutant) + SARS-Cov-2 spike glycoprotein <br />
**[[7a91]], [[7a92]], [[7a94]], [[7a95]], [7a96]], [[7a97]], [[7a98]], [[7bh9]], [[7ct5]], [[7ddo]], [[7ddp]], [[7df4]], [[7dqa]], [[7dx5]], [[7dx6]], [[7dx7]], [[7dx8]], [[7dx9]], [[7edj]], [[7fdg]], [[7fdh]], [[7fdi]], [[7fem]], [[7kj2]], [[7kj3]], [[7kj4]], [[7kmb]], [[7kms]], [[7kmz]], [[7knb]], [[7kne]], [[7knh]], [[7kni]], [[7l7f]], [[7mjm]], [[7mjn]], [[7p8j]], [[7r0z]], [[7r10]], [[7r11]], [[7r12]], [[7r1a]], [[7t9k]], [[7t9l]], [[7tew]], [[7tex]], , [[7tez]], [[7te0]], [[7v7z]], [[7v80]], [[7v81]], [[7v82]], [[7v83]], [[7v84]], [[7v85]], [[7v86]], [[7v89]], [[7v8a]], [[7v8b]], [[7vx4][[7vx5]], [[7vx9]], [[7vxa]], [[7vxb]], [[7vxc]], [[7vxd]], [[7vxf]], [[7vxk]], [[7vxm]], [[7w8s]], [[7w98]], [[7w99]], [[7w9b]], [[7w9c]], [[7w9i]], [[7wa1]], [[7wgb]], [[7wgc]], [[7wk4]], [[7wk5]], [[7wk6]], [[7wpa]], [[7wpb]], [[7wpc]], [[7wri]], [[7ws8]], [[7ws9]], [[7wsa]], [[7wvp]], [[7wvq]], [[7xb0]], [[7xb1]], [[7xch]], [[7xci]], [[7xo7]], [[7xo8]], [[7xo9]], [[7zdq]], [[7zf7]], [[8dlv]], [[8dv1]], [[8dv2]] – hANCE 2 + SARS-Cov-2 spike glycoprotein – Cryo EM<br />
**[[7l0n]], [[7tn0]] – hANCE 2 + SARS-Cov-2 spike glycoprotein + antibody<br />
**[[7dx4]], [[7xcp]], [[7ydi]], [[7yeg]], [[8df5]] – hANCE 2 + SARS-Cov-2 spike glycoprotein + antibody - Cryo EM<br />
**[[7dwx]] – hANCE 2 + Na-dependent neutral amino acid transporter + SARS-Cov-2 spike glycoprotein – Cryo EM<br />
**[[7fc5]], [[7fc6]], [[7w6r]], [[7xby]] – ANCE + SARS-Cov-2 spike glycoprotein – horse<br />
**[[7wsk]] – ANCE + SARS-Cov-2 spike glycoprotein – civet<br />
**[[7c8d]] – cANCE + SARS-Cov-2 spike glycoprotein – cat - Cryo EM<br />
**[[7e3j]] – ANCE + SARS-Cov-2 spike glycoprotein – dog<br />
**[[7fdk]], [[7xo4]], [[7xo5]], [[7xo6]], [[7xoa]], [[7xob]], [[7xoc]] – ANCE + SARS-Cov-2 spike glycoprotein – mouse – Cryo EM<br />
**[[7c8j]] – baANCE + SARS-Cov-2 spike glycoprotein<br />
 
*Angiotensin Converting Enzyme C domain (642-1232)
 
**[[6zpu]] – hANCE 1 (mutant)<br />
**[[3l3n]] – hANCE 1 (mutant) +LISW<br />
**[[3bkk]], [[3bkl]] – hANCE 1 +ketone inhibitor<br />
**[[2oc2]] – hANCE 1 +phosphinic inhibitor<br />
**[[7q28]] – hANCE 1 (mutant) + inhibitor<br />
**[[6h5w]], [[7z70]] - hANCE 1 (mutant) + anti-hypertensive drug<br />
 
*Angiotensin Converting Enzyme residues 30-1240
 
**[[7q4c]] – hANCE 1 30-1240 – Cryo EM<br />
**[[7q3y]], [[7q49]], [[7q4d]], [[7q4e]] – hANCE 1 (mutant) 30-1240 – Cryo EM<br />


*Angiotensin Converting Enzyme C domain (642-1232)  
*Angiotensin Converting Enzyme C domain (642-1232)  
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**[[6h5w]] - hANCE (mutant) + anti-hypertensive drug<br />
**[[6h5w]] - hANCE (mutant) + anti-hypertensive drug<br />


*Angiotensin Converting Enzyme complex
*Angiotensin Converting Enzyme residues 2-805 complex


**[[6m1d]] – hANCE 2 + Na-dependent neutral amino acid transporter – Cryo EM<br />
**[[6m1d]] – hANCE 2 + Na-dependent neutral amino acid transporter – Cryo EM<br />
**[[6m17]], [[6m18]] – hANCE 2 + Na-dependent neutral amino acid transporter + spike glycoprotein – Cryo EM<br />
**[[6m17]], [[6m18]] – hANCE 2 + Na-dependent neutral amino acid transporter + spike glycoprotein – Cryo EM<br />
 
**[[7id]] – hANCE 2 (mutant) + spike glycoprotein – Cryo EM<br />
}}
}}
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Michal Harel
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