2g9n: Difference between revisions

<table><tr><td colspan='2'>[[2g9n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G9N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G9N FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>

[https://www.uniprot.org/uniprot/IF4A1_HUMAN IF4A1_HUMAN] ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.<ref>PMID:19153607</ref> <ref>PMID:19204291</ref>  

[[Category: Homo sapiens]]

[[Category: Arrowsmith C]]

[[Category: Berglund H]]

[[Category: Collins R]]

[[Category: Edwards A]]

[[Category: Ehn M]]

[[Category: Flodin S]]

[[Category: Flores A]]

[[Category: Graslund S]]

[[Category: Hallberg BM]]

[[Category: Hammarstrom M]]

[[Category: Hogbom M]]

[[Category: Holmberg-Schiavone L]]

[[Category: Kotenyova T]]

[[Category: Nilsson-Ehle P]]

[[Category: Nordlund P]]

[[Category: Nyman T]]

[[Category: Ogg D]]

[[Category: Persson C]]

[[Category: Sagemark J]]

[[Category: Stenmark P]]

[[Category: Sundstrom M]]

[[Category: Thorsell AG]]

[[Category: Uppenberg J]]

[[Category: Van Den Berg S]]

[[Category: Weigelt J]]