HPPK 3D structures: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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 **[[1rb0]] – EcHPPK + 6-hydroxymethylpterin-diphosphate <br />
 **[[3hd1]], [[3hsg]], [[3ht0]], [[3ilj]], [[3kuh]] – EcHPPK (mutant) + methyleneadenosine-triphosphate  <br />
-**[[3ud5]], [[3ude]], [[3udv]], [[4f7v]], [[6an4]], [[6an6]] – EcHPPK + inhibitor <br />
+**[[3ud5]], [[3ude]], [[3udv]], [[4f7v]], [[6an4]], [[6an6]], [[7kdo]], [[7kdr]] – EcHPPK + inhibitor <br />
 **[[4pzv]] - HPPK/DHPS + inhibitor - ''Francisella tularensis''<br />
 **[[3qbc]] – SaHPPK + inhibitor – ''Staphylococcus aureus''<br />
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 *HPPK ternary complex
-**[[1ru2]], [[1tmm]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + 6-hydroxymethylpterin <br />
+**[[1ru2]], [[1tmm]] – EcHPPK (mutant) + ATP derivative + 6-hydroxymethylpterin <br />
 **[[1dy3]] – EcHPPK (mutant) + ATP + pteridine derivative <br />
-**[[3ip0]] – EcHPPK + methyleneadenosine-triphosphate + pteridine derivative <br />
+**[[3ip0]] – EcHPPK + ATP derivative + pteridine derivative <br />
-**[[1f9h]], [[1hq2]], [[1q0n]], [[1ru1]], [[3ilo]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + pteridine derivative <br />
+**[[1f9h]], [[1hq2]], [[1q0n]], [[1ru1]], [[3ilo]] – EcHPPK (mutant) + ATP derivative + pteridine derivative <br />
-**[[3hd2]] – EcHPPK (mutant) + methyleneadenosine-triphosphate + pterine  <br />
+**[[3hd2]] – EcHPPK (mutant) + ATP derivative + pterine  <br />
-**[[4m5g]], [[4m5h]], [[4m5i]], [[4m5j]], [[4m5k]], [[4m5l]], [[4m5m]], [[4m5n]] – EcHPPK + methyleneadenosine-triphosphate + inhibitor  <br />
+**[[4m5g]], [[4m5h]], [[4m5i]], [[4m5j]], [[4m5k]], [[4m5l]], [[4m5m]], [[4m5n]] – EcHPPK + ATP derivative + inhibitor  <br />
 **[[1rao]] – EcHPPK (mutant) + AMP + 6-hydroxymethylpterin-diphosphate <br />
 **[[5etl]], [[5etm]], [[5etn]], [[5eto]], [[5etp]], [[5etq]], [[5etr]], [[5ets]], [[5ett]], [[5etv]] - EcHPPK + AMPCPP + inhibitor<br />
 **[[4crj]], [[4cwb]], [[4cyu]] - SaHPPK + AMPCPP + inhibitor<br />
-**[[2qx0]] – HPPK + methyleneadenosine-triphosphate + pteridine derivative – ''Yersinia pestis''<br />
+**[[2qx0]] – HPPK + ATP derivative, [[5etk]], [[5etl]], [[5etm]], [[5etn]], [[5eto]], [[5etp]], [[5etq]], [[5etr]], [[5ets]], [[5ett]], [[5etv]]  + pteridine derivative – ''Yersinia pestis''<br />
+*HPPK-DHPS
+**[[5z79]] – HPPK-DHPS + ATP derivative + pteridine derivative + pterine + adenosine derivative + 4-aminobenzoic acid – ''Plasmodium vivax''<br />
+**[[3mcm]] – FtHPPK-DHPS – ''Francisella tularensis''<br />
+**[[3mcn]] – FtHPPK-DHPS + inhibitor <br />
+**[[4pzv]] – FtHPPK-DHPS + bisubstrate inhibitor <br />
+**[[3mco]] – FtHPPK-DHPS + ATP derivative<br />
+**[[6jwu]], [[6jwx]] – PfHPPK-DHPS + AMP + pteridine derivative – ''Plasmodium falciparum'' <br />
+**[[6jwq]] – PfHPPK-DHPS + ATP + AMP <br />
+**[[6jws]], [[6jwt]] – PfHPPK-DHPS (mutant) + ATP + pteroate <br />
+**[[6jwr]] – PfHPPK-DHPS (mutant) + AMP + pteroate <br />
+**[[6jwz]] – PfHPPK-DHPS (mutant) + AMP + pteridine derivative <br />
+**[[6jwv]], [[6jwy]] – PfHPPK-DHPS (mutant) + ATP + pteridine derivative <br />
+**[[6jww]] – PfHPPK-DHPS (mutant) + ATP + AMP + pteridine derivative <br />
+**[[6kck]] – PfHPPK-DHPS + ATP derivative + pterine + hydroxybenzoate<br />
+**[[6kcl]], [[6kcm]] – PfHPPK-DHPS (mutant) + ATP derivative + pterine + hydroxybenzoate<br />
 }}
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