Protein Hfq: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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-<StructureSection load='4ht9' size='340' side='right' caption='Structure of E. coli trimeric Hfq  complex with poly(A) RNA (yellow, cyan) and poly(U) RNA (magenta, green) (PDB code [[4ht9]])' scene='87/875687/Cv/1'>
+<StructureSection load='4ht9' size='340' side='right' caption='Structure of E. coli hexameric Hfq  complex with poly(A) RNA and poly(U) RNA (PDB code [[4ht9]])' scene='87/875687/Cv/1'>
 == Function ==
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 == Structural highlights ==
-The 3D structure of the complex between Hfq and poly(A) RNA and poly(U) RNA shows the poly(A) binding at the distal face of Hfq and poly(U) binding at its proximal face.  For the poly(A) A-R-N binding site the A site shows hydrogen bonding to Gln and Lys.  The R site shows stacking interactions as well as hydrogen bonding.  The N site does not show any interaction.  The poly(U) binding site of Hfq is a classical uridine binding pocket with both stacking and hydrogen bonding interactions<ref>PMID:23605038</ref>.
+The biological assembly of Protein Hfq from ''E. coli'' is <scene name='87/875687/Cv/2'>homohexamer</scene> (PDB code [[4ht9]]). The 3D structure of the complex between Hfq and poly(A) RNA and poly(U) RNA shows the poly(A) binding at the distal face of Hfq and poly(U) binding at its proximal face. For the poly(A) A-R-N binding site the A site shows hydrogen bonding to Gln and Lys.  The R site shows stacking interactions as well as hydrogen bonding. The N site does not show any interaction.  The poly(U) binding site of Hfq is a classical uridine binding pocket with both stacking and hydrogen bonding interactions<ref>PMID:23605038</ref>.
 </StructureSection>