SARS-CoV-2 spike protein mutations: Difference between revisions
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===Virulence Increase Uncertain=== | ===Virulence Increase Uncertain=== | ||
An early report found that B.1.1.7 does not increase hospitalization or death compared to the wild type SARS-CoV-2<ref name="phe1" />. Later evidence raised a "realistic possibility" of increased mortality<ref name="hornby1">[https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/955239/NERVTAG_paper_on_variant_of_concern__VOC__B.1.1.7.pdf NERVTAG note on B.1.1.7 severity], Peter Horby ''et al.'', January 18, 2021.</ref><ref name="reutersUKdeath">[https://www.businessinsider.com/why-uk-coronavirus-variant-may-be-deadlier-2021-1 UK officials say people who get the contagious coronavirus variant may have a higher risk of death.] Aylin Woodward for Reuters, January 25, 2021.</ref>. Morbidity and mortality for the other variant lineages remains under investigation. | An early report found that B.1.1.7 does not increase hospitalization or death compared to the wild type SARS-CoV-2<ref name="phe1" />. Later evidence raised a "realistic possibility" of increased mortality<ref name="hornby1">[https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/955239/NERVTAG_paper_on_variant_of_concern__VOC__B.1.1.7.pdf NERVTAG note on B.1.1.7 severity], Peter Horby ''et al.'', January 18, 2021.</ref><ref name="reutersUKdeath">[https://www.businessinsider.com/why-uk-coronavirus-variant-may-be-deadlier-2021-1 UK officials say people who get the contagious coronavirus variant may have a higher risk of death.] Aylin Woodward for Reuters, January 25, 2021.</ref>. An analysis of statistics in February, 2021, by the UK Government ''New and Emerging Respiratory Virus Threats Advisory Group'' (NERVTAG) concluded that "it is likely that infection with VOC B.1.1.7 is | ||
associated with an increased risk of hospitalisation and death"<ref name="nervtag2">[https://www.gov.uk/government/publications/nervtag-update-note-on-b117-severity-11-february-2021 NERVTAG: Update note on B.1.1.7 severity, 11 February 2021].</ref> | |||
Morbidity and mortality for the other variant lineages remains under investigation. | |||
===National Borders Temporarily Closed=== | ===National Borders Temporarily Closed=== | ||