Nuclear receptors: Difference between revisions
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Nuclear receptor structure is composed of 5 domains - <br /> | Nuclear receptor structure is composed of 5 domains - <br /> | ||
A/B: N-terminal regulatory domain contains activation function 1 (residues 101-370), | A/B: N-terminal regulatory domain contains activation function 1 (residues 101-370), activation function 5 (residues 360-485) and dimerization surface (residues 1-36 and 370-494).<br /> | ||
C: DNA binding domain (DBD)<br /> | C: DNA binding domain (DBD)<br /> | ||
D: Hinge region between DBD and LBD<br /> | D: Hinge region between DBD and LBD<br /> | ||
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F: C-terminal domain | F: C-terminal domain | ||
'''Family members''' (~ according to [https://en.wikipedia.org/wiki/Nuclear_receptor]) | '''Family members''' (~ according to [https://en.wikipedia.org/wiki/Nuclear_receptor|Wikipedia Nuclear receptor]]) | ||
=Thyroid Hormone Receptor-like= | =Thyroid Hormone Receptor-like= | ||
==[[Thyroid hormone receptor]]== | ==[[Thyroid hormone receptor]]== | ||