6ib6: Difference between revisions
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==Solution structure of the water-soluble LU-domain of human Lypd6 protein== | ==Solution structure of the water-soluble LU-domain of human Lypd6 protein== | ||
<StructureSection load='6ib6' size='340' side='right'caption='[[6ib6 | <StructureSection load='6ib6' size='340' side='right'caption='[[6ib6]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6ib6]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6ib6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IB6 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ib6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ib6 OCA], [https://pdbe.org/6ib6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ib6 RCSB], [https://www.ebi.ac.uk/pdbsum/6ib6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ib6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/LYPD6_HUMAN LYPD6_HUMAN] Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Inhibits nicotine-induced Ca(2+) influx through nAChRs (PubMed:27344019). Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity).[UniProtKB:Q66IA6]<ref>PMID:27344019</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Kulbatskii | [[Category: Kulbatskii DS]] | ||
[[Category: Lyukmanova | [[Category: Lyukmanova EN]] | ||
[[Category: Paramonov | [[Category: Paramonov AS]] | ||
[[Category: Shenkarev | [[Category: Shenkarev ZO]] | ||
[[Category: Tsarev | [[Category: Tsarev AV]] | ||