Anterior gradient protein: Difference between revisions
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== Anterior Gradient Protein 2 == | == Anterior Gradient Protein 2 == | ||
<StructureSection load='2LNS' size='350' side='right' caption='residues 41-175 of AGR2 in dimer form (PDB entry [[2lns]])' scene='87/872187/Agr2_full/1'> | <StructureSection load='2LNS' size='350' side='right' caption='residues 41-175 of AGR2 in dimer form (PDB entry [[2lns]])' scene='87/872187/Agr2_full/1'> | ||
[https://www.uniprot.org/uniprot/O95994] | |||
Originally discovered in Xenopus laevis as a cement gland differentiation regulator, <scene name='87/872187/Agr2_full/1'>Anterior Gradient Protein</scene> (AGR2) in humans is a protein chaperone involved in proteostasis, mainly for proteins expressed in epithelial cells, such as in the esophagus or lungs. AGR2, composed of 175 amino acids, belongs to the protein disulfide isomerase family (PDI). | Originally discovered in Xenopus laevis as a cement gland differentiation regulator, <scene name='87/872187/Agr2_full/1'>Anterior Gradient Protein</scene> (AGR2) in humans is a protein chaperone involved in proteostasis, mainly for proteins expressed in epithelial cells, such as in the esophagus or lungs. AGR2, composed of 175 amino acids, belongs to the protein disulfide isomerase family (PDI). | ||
== Structural highlights == | == Structural highlights == | ||