1wgq: Difference between revisions

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<StructureSection load='1wgq' size='340' side='right'caption='[[1wgq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1wgq' size='340' side='right'caption='[[1wgq]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wgq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WGQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1WGQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wgq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WGQ FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 4933427A08 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 4933427A08 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1wgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wgq OCA], [http://pdbe.org/1wgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wgq RCSB], [http://www.ebi.ac.uk/pdbsum/1wgq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wgq ProSAT], [http://www.topsan.org/Proteins/RSGI/1wgq TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wgq OCA], [https://pdbe.org/1wgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wgq RCSB], [https://www.ebi.ac.uk/pdbsum/1wgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wgq ProSAT], [https://www.topsan.org/Proteins/RSGI/1wgq TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FGD6_MOUSE FGD6_MOUSE]] May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity).  
[[https://www.uniprot.org/uniprot/FGD6_MOUSE FGD6_MOUSE]] May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity).  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 09:54, 2 March 2022

Solution Structure of the Pleckstrin Homology Domain of Mouse Ethanol Decreased 4 ProteinSolution Structure of the Pleckstrin Homology Domain of Mouse Ethanol Decreased 4 Protein

Structural highlights

1wgq is a 1 chain structure with sequence from Lk3 transgenic mice. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:RIKEN cDNA 4933427A08 (LK3 transgenic mice)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[FGD6_MOUSE] May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. May play a role in regulating the actin cytoskeleton and cell shape (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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