1qk5: Difference between revisions

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<StructureSection load='1qk5' size='340' side='right'caption='[[1qk5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='1qk5' size='340' side='right'caption='[[1qk5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1qk5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii_rh Toxoplasma gondii rh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QK5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1QK5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1qk5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii_RH Toxoplasma gondii RH]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QK5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dbr|1dbr]], [[1hmp|1hmp]], [[1qk3|1qk3]], [[1qk4|1qk4]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qk5 OCA], [https://pdbe.org/1qk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qk5 RCSB], [https://www.ebi.ac.uk/pdbsum/1qk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qk5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1qk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qk5 OCA], [http://pdbe.org/1qk5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qk5 RCSB], [http://www.ebi.ac.uk/pdbsum/1qk5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1qk5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HGXR_TOXGO HGXR_TOXGO]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine.<ref>PMID:11188695</ref>
[https://www.uniprot.org/uniprot/HGXR_TOXGO HGXR_TOXGO] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine.<ref>PMID:11188695</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hypoxanthine phosphoribosyltransferase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Toxoplasma gondii rh]]
[[Category: Toxoplasma gondii RH]]
[[Category: Borhani, D W]]
[[Category: Borhani DW]]
[[Category: Davis, R L]]
[[Category: Davis RL]]
[[Category: Heroux, A]]
[[Category: Heroux A]]
[[Category: Ross, L J]]
[[Category: Ross LJ]]
[[Category: White, E L]]
[[Category: White EL]]
[[Category: Glycosyltransferase]]
[[Category: Purine salvage]]
[[Category: Transferase]]

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