Ankyrin repeat domain-containing protein: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Function == | == Function == | ||
'''Ankyrin repeat domain-containing protein''' (ARDCP) recruits kinesin to the cell cortex in order to control microtubule growth via its ankyrin domain<ref>PMID:29183992</ref>. | '''Ankyrin repeat domain-containing protein''' (ARDCP) recruits kinesin to the cell cortex in order to control microtubule growth via its ankyrin domain<ref name="Guo">PMID:29183992</ref>. | ||
== Disease == | == Disease == | ||
| Line 11: | Line 11: | ||
== Structural highlights == | == Structural highlights == | ||
The 3D structure of the complex between human ARDCP 25 C-terminal and a kinesin peptide shows 2 types of interactions. Kinesin residues KARR interact in an acidic pocket and residues QMELLYA interact in a hydrophobic pocket<ref | The 3D structure of the complex between human ARDCP 25 C-terminal and a kinesin peptide shows 2 types of interactions. Kinesin residues KARR interact in an acidic pocket and residues QMELLYA interact in a hydrophobic pocket<ref name="Guo"/>. | ||
</StructureSection> | </StructureSection> | ||