Neuraminidase 3D structures: Difference between revisions
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**[[3h71]] - SpNANA catalytic domain precursor<br /> | **[[3h71]] - SpNANA catalytic domain precursor<br /> | ||
**[[4zxk]] - SpNANA carbohydrate-binding domain<br /> | **[[4zxk]] - SpNANA carbohydrate-binding domain<br /> | ||
**[[4yz4]], [[4yw4]] – SpNANC<br /> | **[[4yz4]], [[4yw4]] – SpNANC<br /> | ||
**[[2xzi]], [[2xzj]], [[2xzk]], [[2xcy]] – NANA – ''Aspergillus fumigatus''<br /> | **[[2xzi]], [[2xzj]], [[2xzk]], [[2xcy]] – NANA – ''Aspergillus fumigatus''<br /> | ||
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**[[1euu]] - MvNANA residues 47-647 <br /> | **[[1euu]] - MvNANA residues 47-647 <br /> | ||
**[[1wcq]], [[1w8n]], [[1w8o]], [[2hu0]], [[2hu4]] – MvNANA residues 47-647 (mutant) <br /> | **[[1wcq]], [[1w8n]], [[1w8o]], [[2hu0]], [[2hu4]] – MvNANA residues 47-647 (mutant) <br /> | ||
**[[3sil]] – StNANA (mutant) – ''Salmonella typhimurium''<br /> | **[[3sil]], [[6trg]], [[7af2]] – StNANA (mutant) – ''Salmonella typhimurium''<br /> | ||
**[[4bbw]], [[5muk]] – BtNAN – ''Bacterioides thetaiotaomicron''<br /> | **[[4bbw]], [[5muk]] – BtNAN – ''Bacterioides thetaiotaomicron''<br /> | ||
**[[5tsp]] - NANI + CHES – ''Clostridium perfringens''<br /> | **[[5tsp]] - NANI + CHES – ''Clostridium perfringens''<br /> | ||
**[[6mrx]] - baNANA - bacterium<br /> | |||
*Binary complexes | *Binary complexes | ||
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**[[2ya7]], [[2ya8]], [[5kky]], [[5f9t]] - SpNANA catalytic domain + inhibitor<br /> | **[[2ya7]], [[2ya8]], [[5kky]], [[5f9t]] - SpNANA catalytic domain + inhibitor<br /> | ||
**[[2ya6]]- SpNANA catalytic domain + sialic acid analog<br /> | **[[2ya6]]- SpNANA catalytic domain + sialic acid analog<br /> | ||
**[[4yz2]], [[4yw3]], [[4wy2]], [[4wy1]] – SpNANC + inhibitor<br /> | **[[4yz2]], [[4yw3]], [[4wy2]], [[4wy1]] – SpNANC + inhibitor<br /> | ||
**[[4yw1]] – SpNANC residues 83-740 + sialic acid + neuraminic acid derivative <br /> | **[[4yw1]] – SpNANC residues 83-740 + sialic acid + neuraminic acid derivative <br /> | ||
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**[[1dil]], [[1dim]] – StNANA + inhibitor<br /> | **[[1dil]], [[1dim]] – StNANA + inhibitor<br /> | ||
**[[2sim]], [[2sil]] - StNANA + neuraminic acid derivative<br /> | **[[2sim]], [[2sil]] - StNANA + neuraminic acid derivative<br /> | ||
**[[6tvi]] - StNANA (mutant) + neuraminic acid derivative<br /> | |||
**[[5mul]] – BtNAN + glucuronic acid<br /> | **[[5mul]] – BtNAN + glucuronic acid<br /> | ||
**[[6myv]] - baNANA + neuraminic acid derivative <br /> | |||
*'''Influenza virus neuraminidase''' | *'''Influenza virus neuraminidase''' | ||
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**[[2ht5]] – IvNAN N8 residues 82-469<br /> | **[[2ht5]] – IvNAN N8 residues 82-469<br /> | ||
**[[6hfc]], [[6d3b]] – IvNAN N9<br /> | **[[6hfc]], [[6d3b]] – IvNAN N9<br /> | ||
**[[7nn9]] - IvNAN N9 Tern <br /> | |||
**[[2qwa]] - IvNAN N9 Tern (mutant)<br /> | **[[2qwa]] - IvNAN N9 Tern (mutant)<br /> | ||
**[[6crd]] - IvNAN N9 Tern/tetrabrachion <br /> | |||
**[[7cm1]] - IvNAN - toad<br /> | |||
*Binary complexes of Influenza virus neuraminidase | *Binary complexes of Influenza virus neuraminidase | ||
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**[[1f8b]], [[1inv]], [[1inw]], [[1inx]], [[1iny]], [[4gb1]] – IvNANA + sialic acid analog<br /> | **[[1f8b]], [[1inv]], [[1inw]], [[1inx]], [[1iny]], [[4gb1]] – IvNANA + sialic acid analog<br /> | ||
**[[3ti3]], [[3ti4]], [[3ti5]], [[3ti6]], [[6g02]], [[6g01]] - IvNAN H1n1 + inhibitor<br /> | **[[3ti3]], [[3ti4]], [[3ti5]], [[3ti6]], [[6g02]], [[6g01]] - IvNAN H1n1 + inhibitor<br /> | ||
**[[4qnp]], [[6q23]] - IvNAN H1n1 + antibody<br /> | **[[4qnp]], [[6q23]], [[6lxi]], [[6lxk]] - IvNAN H1n1 + antibody<br /> | ||
**[[3tia]], [[3tib]], [[3tic]] – IvNAN H2n2 + inhibitor<br /> | **[[3tia]], [[3tib]], [[3tic]] – IvNAN H2n2 + inhibitor<br /> | ||
**[[6q20]] - IvNAN H2n2 + antibody<br /> | **[[6q20]] - IvNAN H2n2 + antibody<br /> | ||
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**[[2htr]], [[2htw]] – IvNAN H5n1 + sialic acid analog<br / | **[[2htr]], [[2htw]] – IvNAN H5n1 + sialic acid analog<br / | ||
**[[5l18]] - IvNAN H7n9 + sialic acid<br /> | **[[5l18]] - IvNAN H7n9 + sialic acid<br /> | ||
**[[6q1z]], [[6pzf]], [[6pzw]], [[6pzy]], [[6pzz]] - IvNAN H7n9 + antibody<br /> | **[[6lxj]], [[6q1z]], [[6pzf]], [[6pzw]], [[6pzy]], [[6pzz]] - IvNAN H7n9 + antibody<br /> | ||
**[[6u02]] - IvNAN H7n9 + antibody – Cryo EM<br /> | **[[6u02]] - IvNAN H7n9 + antibody – Cryo EM<br /> | ||
**[[6pze]] - IvNAN H7n9 (mutant) + antibody<br /> | **[[6pze]] - IvNAN H7n9 (mutant) + antibody<br /> | ||
**[[6v4n]], [[6v4o]] - IvNAN + antibody – Cryo EM<br /> | |||
**[[1nna]], [[1nnb]], [[5w2y]], [[5w2w]], [[5w2u]], [[5w26]] - IvNAN H11n9 + neuraminic acid derivative<br /> | **[[1nna]], [[1nnb]], [[5w2y]], [[5w2w]], [[5w2u]], [[5w26]] - IvNAN H11n9 + neuraminic acid derivative<br /> | ||
**[[4dgr]] - IvNAN H11n9 + benzoic acid derivative<br /> | **[[4dgr]] - IvNAN H11n9 + benzoic acid derivative<br /> | ||
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**[[4mwq]], [[4mwr]], [[4mwu]], [[4mwv]], [[4mww]], [[4mwx]], [[4mwy]], [[4mx0]] - IvNAN H7n9 + flu drug<br /> | **[[4mwq]], [[4mwr]], [[4mwu]], [[4mwv]], [[4mww]], [[4mwx]], [[4mwy]], [[4mx0]] - IvNAN H7n9 + flu drug<br /> | ||
**[[4qn7]]- IvNAN H10n7 + drug<br /> | **[[4qn7]]- IvNAN H10n7 + drug<br /> | ||
**[[3san]], [[3ti8]] - IvNAN H12N5 + flu drug<br /> | **[[3san]], [[3ti8]], [[7e6q]] - IvNAN H12N5 + flu drug<br /> | ||
**[[4hzw]], [[4hzx]] - IvNAN N3 + flu drug<br /> | **[[4hzw]], [[4hzx]] - IvNAN N3 + flu drug<br /> | ||
**[[4hzz]], [[4i00]] - IvNAN N3 (mutant) + flu drug<br /> | **[[4hzz]], [[4i00]] - IvNAN N3 (mutant) + flu drug<br /> | ||
**[[6hg5]] - IvNAN N6 + flu drug<br /> | **[[6hg5]] - IvNAN N6 + flu drug<br /> | ||
**[[6hfy]] - IvNAN N6 + | **[[6hfy]] - IvNAN N6 + neuraminic acid derivative<br /> | ||
**[[6heb]], [[6hcx]] - IvNAN N9 + flu drug<br /> | **[[6heb]], [[6hcx]] - IvNAN N9 + flu drug<br /> | ||
**[[6hg0]] - IvNAN N9 Tern + NANA<br /> | **[[6hg0]] - IvNAN N9 Tern + NANA<br /> | ||
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**[[2sli]], [[1sli]], [[3sli]] – lTS + inhibitor – leech<br /> | **[[2sli]], [[1sli]], [[3sli]] – lTS + inhibitor – leech<br /> | ||
**[[1mr5]], [[1ms3]], [[1ms4]] - TcTS (mutant) – ''Trypanosoma cruzi''<br /> | **[[1mr5]], [[1ms3]], [[1ms4]] - TcTS (mutant) – ''Trypanosoma cruzi''<br /> | ||
**[[1ms0]] - TcTS (mutant) + | **[[1ms0]] - TcTS (mutant) + neuraminic acid derivative + lactose<br /> | ||
**[[1ms1]], [[1ms8]] - TcTS (mutant) + | **[[1ms1]], [[1ms8]] - TcTS (mutant) + neuraminic acid derivative <br /> | ||
**[[3b69]] - TcTS (mutant) + NANA derivative<br /> | **[[3b69]] - TcTS (mutant) + NANA derivative<br /> | ||
**[[1ms5]] - TcTS (mutant) + Na-S-Gal<br /> | **[[1ms5]] - TcTS (mutant) + Na-S-Gal<br /> | ||
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**[[3opz]] - TcTS (mutant) + antibody<br /> | **[[3opz]] - TcTS (mutant) + antibody<br /> | ||
**[[2ah2]] - TcTS (mutant) + difluorosialic acid<br /> | **[[2ah2]] - TcTS (mutant) + difluorosialic acid<br /> | ||
*'''Neuraminidase B or sialidase B''' | |||
**[[2vw0]], [[2vw1]], [[2vw2]] – SpNANB<br /> | |||
**[[4xhb]], [[4xik]], [[4xio]], [[4xjz]], [[4xmi]] - SpNANB (mutant) <br /> | |||
**[[4foq]], [[4fov]], [[4fow]], [[4foy]], [[4fp2]], [[4fp3]], [[4fpc]], [[4fpe]], [[4fpf]], [[4fpg]], [[4fph]], [[4fpj]], [[4fpk]], [[4fpl]], [[4fpo]], [[4fpy]], [[4fq4]], [[4xe9]], [[4xhx]], [[4xil]], [[4xj9]], [[4xja]], [[4xju]], [[4xjw]], [[4xma]] - SpNANB (mutant) + inhibitor<br /> | |||
**[[4xog]] - SpNANB (mutant) + neuraminic acid derivative + inhibitor<br /> | |||
**[[2jkb]], [[4xj8]] - SpNANB residues 30-697 + sialic acid analog<br /> | |||
**[[4c1w]] - SpNANB residues 52-236 + sialic acid derivative<br /> | |||
**[[4xyx]] – SpNANB + drug<br /> | |||
**[[4yw2]] – SpNANB residues 83-740 + sialic acid<br /> | |||
*'''Anhydrosialidase''' | *'''Anhydrosialidase''' | ||