5mz4: Difference between revisions

<table><tr><td colspan='2'>[[5mz4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Csfv Csfv]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5lkl 5lkl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MZ4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MZ4 FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5lkl|5lkl]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mz4 OCA], [http://pdbe.org/5mz4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mz4 RCSB], [http://www.ebi.ac.uk/pdbsum/5mz4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mz4 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/POLG_CSFVA POLG_CSFVA]] E(rns), E1 and E2 are responsible of cell attachment and subsequent fusion of viral and cellular membrane.  P7 forms a leader sequence to properly orient NS2 in the membrane.  Uncleaved NS2-3 is required for production of infectious virus.  NS2 protease seems to play a vital role in viral RNA replication control and in the pathogenicity of the virus.[PROSITE-ProRule:PRU01029]  NS3 displays three enzymatic activities: serine protease, NTPase and RNA helicase.  NS4A is a cofactor for the NS3 protease activity.  RNA-directed RNA polymerase NS5 replicates the viral (+) and (-) genome.[PROSITE-ProRule:PRU00539]  

[[Category: Rey, F A]]

[[Category: Tortorici, M A]]

[[Category: Viral protein]]