SARS-CoV-2 spike protein fusion transformation: Difference between revisions
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==Preventing Fusion with Drugs== | ==Preventing Fusion with Drugs== | ||
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Graphical Abstract from Romeo, Iacovelli & Falconi<ref name="romeo" /> reproduced in accord with the COVID-19 pandemic license of Elsevier<ref name="elsevier">This quote is from the PubMedCentral version of the Romeo paper, after you click ''License Information'': Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</ref>. Permission also given by Mattia Falconi, August 12, 2020. | |||
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SARS-CoV-2 spike protein has two interior cavities: (i) <scene name='85/857791/6zgi_translucent_backbone/2'>Show spike protein structure</scene> ([[6zgi]]) and then (ii) | SARS-CoV-2 spike protein has two interior cavities: (i) <scene name='85/857791/6zgi_translucent_backbone/2'>Show spike protein structure</scene> ([[6zgi]]) and then (ii) | ||
<jmol> | <jmol> | ||